Results 31 to 40 of about 73,929 (196)

Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia

Microorganisms, 2021
The skin microbiome and sebum may be associated with inflammation-related diseases of the scalp. To assess the pathogenesis and progression of androgenetic alopecia (AGA), we analyzed the composition of sebum and the bacterial and fungal microbiomes of ...
Kazuhiro Suzuki, Mizuna Inoue, Otomi Cho, Rumiko Mizutani, Yuri Shimizu, Tohru Nagahama, Takashi Sugita   +6 more
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Simultaneous determination of concentration of sulfamethoxazole and trimethoprim in human plasma by dual-quaternary HPLC and its clinical application

Precision Medication
Sulfamethoxazole compound, a combination of sulfamethoxazole and trimethoprim, is commonly prescribed to organ transplant recipients for infections caused by Nocardia, Burkholderia cepacia, and Pneumocystis jirovecii.
Li Nong, Yunxia Tang, Xiaoning Qin, Zhou Zhou, Zongqiang Lai, WenXing Wei, Wenwen Tan   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Anti-platelet aggregation effect of Compound Danshen dripping pill: An integrated study of meta-analysis, network pharmacology, and in vivo and vitro experiments

Precision Medication
Objective: Compound Danshen Dripping Pill (CDDP) is a marketed Chinese patent medicine, primarily efficacious in “promoting blood circulation to remove blood stasis, regulating Qi to relieve pain”.
Bo Pang, Haofan Xu, Zhouyi Xie, Yi Chen, Yu Wei, Mengying Zhang, Qian Zhao, Wenjia Wang, Jingbo Zhai, Yunhui Hu   +9 more
doaj   +1 more source

Improving the understanding of originator and biosimilar biologics among healthcare providers in Saudi Arabia

Saudi Pharmaceutical Journal, 2020
The loss of patentability of many originator biologics has led to the rapid introduction of biosimilar agents. The anticipated economic benefit of introducing such agent has been accompanied by vagueness surrounding their biotechnology, approval ...
Mohammed A. Omair, Tariq Alhawassi, Munira Alwaihibi, Ghada Aldrees, Mahmoud Mosli, Wesam M. Asser, Maryam A. Alharaibi, Atheer T. Alotaibi, Doaa A. Bintaleb, Najah K. Alharbi, Ahmed Z. Alotaibi, Wajed A. Alshammari, Nouf Alanazi, Ali M. Asiri, Rana Almadany, Hanan Al Rayes, Turki Al-Thunian, Moureq Alotaibi, Abdulrazaq Al Jazaeri   +18 more
doaj   +1 more source

Effectiveness of BNT162b2 after extending the primary series dosing interval in children and adolescents aged 5–17

Nature Communications, 2023
Extending the interval between doses of mRNA Covid-19 vaccines has been linked with a reduced risk of myocarditis in children and adolescents, but impacts on vaccine effectiveness are not known. Here, the authors perform a nested case-control study using
Francisco Tsz Tsun Lai, Min Fan, Caige Huang, Celine Sze Ling Chui, Eric Yuk Fai Wan, Xue Li, Carlos King Ho Wong, Ching-Lung Cheung, Ian Chi Kei Wong, Esther Wai Yin Chan   +9 more
doaj   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Impact of a delayed second dose of mRNA vaccine (BNT162b2) and inactivated SARS-CoV-2 vaccine (CoronaVac) on risks of all-cause mortality, emergency department visit, and unscheduled hospitalization

BMC Medicine, 2022
Background Safety after the second dose of the SARS-CoV-2 vaccine remains to be elucidated, especially among individuals reporting adverse events after their first dose.
Carlos King Ho Wong, Xi Xiong, Kristy Tsz Kwan Lau, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Xue Li, Esther Wai Yin Chan, Eric Yuk Fai Wan, Ivan Chi Ho Au, Benjamin John Cowling, Cheuk Kwong Lee, Ian Chi Kei Wong   +11 more
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source