Results 71 to 80 of about 964,739 (287)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Association between medication adherence to chronic diseases and shift-work schedules in the Korean working population

Scientific Reports, 2022
Shift-working schedules are closely linked to chronic diseases, and only a few studies have investigated the association between working schedules and medication adherence in chronic diseases targeting workers.
Seung-Yeon Lee, Seunghyun Lee, Wanhyung Lee   +2 more
doaj   +1 more source

Medication Adherence in Children with Asthma

Patient Preference and Adherence
Asthma is the most common chronic disease in childhood. If untreated, asthma can lead to debilitating daily symptoms which affect quality of life, but more importantly can lead to fatal asthma attacks which unfortunately still occur globally. The most effective treatment strategy for controlling asthma is for the patient to follow a personalised asthma
Paddy McCrossan, Michael Shields, James McElnay   +2 more
openaire   +4 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Traditional complementary and alternative medicine and antiretroviral treatment adherence among HIV patients in Kwazulu-Natal, South Africa. [PDF]

, 2009
Adherence to antiretroviral medication in the treatment of HIV is critical, both to maximize efficacy and to minimize the emergence of drug resistance.
Ramlagan, Shandir, Anderson, Jane, Fomundam, H, Fomundam, Henry, H Fomundam, Anderson, J, Peltzer, Karl, J Anderson, N Friend-du Preez, K Peltzer, S Ramlagan, Peltzer, K, Friend-du Preez, Natalie, Friend-du Preez, N, Ramlagan, S, Mayura SHIMURA, Kazue KANDA, Katsuhiko SUZUKI, Harumi HAYASHIDA, Kaoru SUGAMA   +19 more
core   +1 more source

Affecting Factors in Medication Adherence in Kidney Transplant Recipients

, 2022
Objective: This study aimed to determine the risk factors related to immunosuppressive medication adherence in kidney transplant recipients. Methods: The study adopted a retrospective design. It was carried out on 208 kidney transplant recipients.
SARIGÖL ORDİN, YAPRAK, DURMAZ EDEER, AYLİN, Nermin Ertan, Özgül Karayurt, Aylin Durmaz Edeer, Karayurt, Ozgul, Serkan Yildiz, Yildiz, Serkan, Yaprak Sarigol Ordin, Ertan, Nermin, Yaprak Sarıgöl Ordin, Serkan Yıldız, Ordin, Yaprak Sarigol, Edeer, Aylin Durmaz   +13 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effectiveness of Interprofessional Collaboration with Pharmacists on Medication Adherence: A Systematic Review [paper] [PDF]

, 2023
School of Nursing CapstonesIntroduction: Medication adherence is a growing healthcare concern. Medication adherence can impact a patient’s health, affect their overall care and causes an increase in healthcare costs.
Fulk, Melanie
core   +1 more source