Results 71 to 80 of about 534,265 (348)

Learning from successes: designing medication adherence intervention research so that we can learn what works and why [PDF]

, 2021
Sara Garfield, Gaby Judah
openalex   +1 more source

Predictors of Medication Adherence and Blood Pressure Control among Saudi Hypertensive Patients Attending Primary Care Clinics: A Cross-Sectional Study [PDF]

, 2017
Purpose To assess the level of medication adherence and to investigate predictors of medication adherence and blood pressure control among hypertensive patients attending primary healthcare clinics in Makkah, Saudi Arabia.
A Alhewiti, A Lehmann, A Ramli, AA Saeed, AD Hyre, AD Oliveira-Filho, C Mahler, CD Kang, DE Morisky, DE Morisky, F Alsolami, GS De, HM Phatak, J Jin, JE Neter, JG Meinema, L Osterberg, LS Al-Sowielem, M Burnier, M Fernandez-Arias, M Manteuffel, M Yassine, MA Krousel-Wood, Mahmoud M. A. Mohamed, MIH Mahmoud, MM Al-Nozha, Muhammad Abdul Hadi, Noel Christopher Barengo, PA James, R Al-Ramahi, R Khatib, Raghda S. Hyat Alhazmi, SA Khalil, Salwa M. Saeed Khayyat, Sarah M. Khayyat, TM Frisoli   +35 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Transient improvement of urticaria induces poor adherence as assessed by Morisky Medication Adherence Scale-8. [PDF]

, 2015
Poor adherence to medication is a major public health challenge. Here, we aimed to determine the adherence to oral and topical medications and to analyze underlying associated factors using the translated Japanese version of Morisky Medication Adherence ...
Abe, Masatoshi, Abe, Shinya, Furue, Masutaka, Hagihara, Akihito, Hiragun, Takaaki, Imafuku, Shinichi, Inomata, Naoko, Kaneko, Sakae, Katoh, Norito, Kitami, Yuki, Kobayashi, Miwa, Masuda, Koji, Morisky, Donald E, Murota, Hiroyuki, Onozuka, Daisuke, Saeki, Hidehisa, Shintani, Yoichi, Sugaya, Makoto, Takeuchi, Satoshi, Tanioka, Miki, Tsunemi, Yuichiro   +20 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Heart Failure Anticoagulation Teach-Back Education and Readmissions [PDF]

, 2020
: Heart failure affects millions of Americans each year. Treatment of advanced heart failure with reduced ejection fraction and left ventricular failure is sometimes treated with implantation of a left-ventricular assist device.

core  

Current Situation of Medication Adherence in Hypertension [PDF]

, 2017
Despite increased awareness, poor adherence to treatments for chronic diseases remains a global problem. Adherence issues are common in patients taking antihypertensive therapy and associated with increased risks of coronary and cerebrovascular events ...
Antoniou, Sotiris, Burnier, Michel, Sierra, Alejandro de la, Volpe, Massimo, Vrijens, Bernard   +4 more
core   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Influencing Factors for Medication Experience and Medication Adherence in Elderly Patients with Chronic Diseases [PDF]

Zhongguo quanke yixue
Background With the accelerated population aging, the number of elderly patients with chronic diseases is growingly elevated. Adherence to medication regimens is pivotal for the health outcomes of chronic diseases.
GAO Min, LI Xiaona, SHI Yongli, LI Ziyuan, DONG Ping, FENG Zhiqiang, MA Dongping, YIN Wenqiang, CHEN Zhongming
doaj   +1 more source