Results 91 to 100 of about 3,978,330 (371)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

GAMBARAN PEMBERIAN OBAT DI INSTALASI GAWAT DARURAT RSUD K.R.M.T WONGSONEGORO SEMARANG [PDF]

open access: yes, 2017
Increasing safety medication is a component of patient’s safety which are lots enough of medication error incident is occurred. Medication error can be preventable by implementing the correct principle in medication treatment.
Rochana, Nana, Solagracia, Glory Ananta
core  

Applying Quality Improvement methods to address gaps in medicines reconciliation at transfers of care from an acute UK hospital [PDF]

open access: yes, 2016
© Published by the BMJ Publishing Group Limited.Objectives Reliable reconciliation of medicines at admission and discharge from hospital is key to reducing unintentional prescribing discrepancies at transitions of healthcare.
Bell, D   +5 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

EVALUASI MEDICATION ERROR PADA PERESEPAN POLIFARMASI PASIEN HIPERTENSI RAWAT INAP DI RSUD DR. ZAINOEL ABIDIN PERIODE FEBRUARI-APRIL 2016 [PDF]

open access: yes, 2016
ABSTRAKEvaluasi medication error telah dilakukan pada resep polifarmasi pasienhipertensi rawat inap di RSUD dr. Zainoel Abidin. Penelitian ini bertujuan untukmenentukan angka kejadian medication error, serta menentukan fase denganangka kejadian tertinggi
Farah Meishara
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Exploring medication error causality and reporting in the Middle East. [PDF]

open access: yes, 2019
The "Medication Without Harm, WHO Global Patient Safety Challenge", published by the World Health Organization in 2017, calls for action to reduce patient harm as a result of unsafe medication practices and medication errors.
Thomas, Binny
core   +1 more source

Medication administration error: magnitude and associated factors among nurses in Ethiopia

open access: yesBMC Nursing, 2015
BackgroundThe significant impact of medication administration errors affect patients in terms of morbidity, mortality, adverse drug events, and increased length of hospital stay. It also increases costs for clinicians and healthcare systems. Due to this,
Senafikish Amsalu Feleke   +2 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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