Results 121 to 130 of about 492,299 (347)

Evaluation of medication errors in one of the largest public hospital: A retrospective study

open access: yesClinical Epidemiology and Global Health
Background: In hospitals, medication errors still occur, especially in developing countries such as Indonesia. However, most incidents can be prevented.
Dewi Susanti Atmaja   +4 more
doaj   +1 more source

Committed to Safety: Ten Case Studies on Reducing Harm to Patients [PDF]

open access: yes, 2006
Presents case studies of healthcare organizations, clinical teams, and learning collaborations to illustrate successful innovations for improving patient safety nationwide.
David Blumenthal, Douglas McCarthy
core  

Bias in observation of medication errors [PDF]

open access: bronze, 1996
Roger M. Gibson   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A Hospital-based Perspective Observational Study on Medication-related Problems in Clinical Practice

open access: yesIndian Journal of Medical Specialities
Background: One of the most significant problems seen during a patient’s hospital stay is medication-related problems (MRPs). MRPs are linked to longer hospital stays, higher healthcare costs, and higher morbidity and mortality rates.
Dhvani Rupeshkumar Dave   +2 more
doaj   +1 more source

Are We Making Smart Pumps Smarter? [PDF]

open access: yes, 2018
Background: Medication errors comprise a significant proportion of medical errors, and are abundant, costly, and associated with causing harm to patients via adverse drug events. The most serious medication errors often involve IV medications.
Schaefer, Brittany
core   +1 more source

Identifying Harm Events in Clinical Care through Medical Narratives

open access: yes, 2017
Preventable medical errors are estimated to be among the leading causes of injury and death in the United States. To prevent such errors, healthcare systems have implemented patient safety and incident reporting systems.
Cohan, Arman   +3 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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