Results 91 to 100 of about 105,382 (285)
Medical Errors: Mandatory Reporting, Voluntary Reporting, or Both? [PDF]
This work evaluates policy recommendations on medical error reporting systems presented in, To err is human, a report published by the Institute of Medicine. Here mandatory reporting should be applied for adverse events, while voluntary reporting is recommended for near misses.
openaire +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A mixed methods investigation of behavioural determinants relating to medication error reporting by health professionals in the United Arab Emirates. [PDF]
Improving the effectiveness and efficiency of medication error reporting is key to enhancing patient safety. The aim of this research was to explore medication error reporting in the United Arab Emirates (UAE), examining the attitudes, beliefs, behaviors
Alqubaisi, Mai
core
National and local medication error reporting systems: a survey of practices in 16 countries [PDF]
OBJECTIVES: To explore the existence and characteristics of national and local medication error reporting (MER) systems and to describe national medication safety experts' perceptions of a good and effective MER system and barriers to reporting. METHODS:
Airaksinen, M. +5 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Knowledge And Attitude Towards Medication Error Reporting Among Undergraduate Nursing Students In Universiti Malaysia Sarawak (Unimas) [PDF]
Introduction: Medication is a licensed drug used to treat medical conditions but misuse of medication can be dangerous and even fatal. Recognizing and understanding medication errors and their causes through reporting systems is crucial.
Nursyafiqah, Abdul Muin
core
Prevalence and causes of prescribing errors : the PRescribing Outcomes for Trainee Doctors Engaged in Clinical Training (PROTECT) study [PDF]
Acknowledgments We would like to express our gratitude to the pharmacists who collected the data, the doctors who participated in interviews and who completed the questionnaire, and the staff at NES for helping us to deliver this research project.
Davey Peter +97 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

