Results 101 to 110 of about 105,382 (285)

Educational Interventions Affecting Medication Error Reporting by Healthcare Professionals in Secondary and Tertiary Care: A Systematic Review and Narrative Synthesis [PDF]

open access: yes
Background Many healthcare systems are striving to improve patient safety, as medication errors are a significant cause of avoidable morbidity and mortality [1].
Jalal, Zahraa; id_orcid   +4 more
core  

Exploring Nurses\u27 Knowledge of Medication Error Reporting [PDF]

open access: yes, 2020
Managing the care of critically ill patients is a highly complex and stressful position requiring high levels of critical thinking skills and judgment. Medical errors, including medication errors continue to happen in hospitals across the nation. Despite
Santos, Karina
core   +1 more source

Reporting of medical errors: time for a reality check [PDF]

open access: yesQuality in Health Care, 2000
Earlier this summer an expert group chaired by the Chief Medical Officer in the UK produced a comprehensive and thoughtful analysis of the current unacceptable state of identifying, analysing, and learning from medical mishaps.1 Although this report, provocatively named An Organisation with a Memory , applies specifically to the UK National Health ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Does Medication Error Reporting Increase With Anonymity? [PDF]

open access: yes, 2010
Medication errors have been a long and growing problem within all health care areas. Prevention and education is the key to prevent the errors from occurring. All efforts must be made to achieve an overall goal of an error-proof health care society.
McCall, Kristina
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The Prevalence, Barriers to Medication Error Reports, and Perceptions of Nurses toward the Causes of Medication Errors in the Hospitals Affiliated to North Khorasan University of Medical Sciences, Iran

open access: yesنشریه پرستاری ایران, 2019
Background & Aims: Medication errors are major healthcare concerns across the world, which cause mortality and physical and psychological complications in patients, their families, and the community every year.
M Ghorbanzadeh   +4 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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