Results 121 to 130 of about 240,410 (292)
Medication errors in emergency departments: is electronic medical record an effective barrier?
Einstein (São Paulo)Objective: To compare medication errors in two emergency departments with electronic medical record, to two departments that had conventional handwritten records at the same organization.
Marina Vaidotas +6 more
doaj +1 more source
A Prescription for Safety: Medication Error Reporting, Education, and Advocating for Change
Patient Safety, 2021 In 1974, pharmacist Michael Cohen learned of a serious adverse event with insulin at a hospital and began sharing information about it with other pharmacists to prevent the error from happening again. Twenty years later, he founded the Institute for Safe
Michael R Cohen, Eugene Myers
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Advancing Patient Safety in the U.S. Department of Veterans Affairs [PDF]
, 2011 As part of a systemwide transformation, the VA formed its National Center for Patient Safety to foster an organizational culture of safety within its nationwide network of hospitals and outpatient clinics.
Deborah Chase, Douglas McCarthy
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Jornal de Assistência Farmacêutica e FarmacoeconomiaOBJECTIVES: The goal of this study is to understand the barriers and incentives to the reporting of medication errors and near misses according to the perception of doctors, nurses and pharmacists, and to explore the understanding of the institution's ...
Juliana Ferreira Fernandes Machado +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Memorial Healthcare System: A Public System Focusing on Patient- and Family-Centered Care [PDF]
, 2010 Outlines a successful multifaceted strategy that includes personalizing healthcare quality, monitoring and reporting of performance data, careful design of care processes, and the system's vertical and horizontal integration.
Jennifer N. Edwards
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source