Results 91 to 100 of about 388,903 (308)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluation of Medication Errors in Hospitalized Patients

مجله كليه طب الكندي, 2012
Objectives: Many medication errors occur in the hospital, and these can endanger patients. The purpose of this study was to evaluate the incidence of medication errors in hospitalized patients, and to categorize the most frequent types of errors, and to
Hamoudi A. Mosah,, Ahmed S. Sahib,, Haedar A. AL-Biati   +2 more
doaj  

Medication errors: classification of seriousness, type, and of medications involved in the reports from a university teaching hospital

Brazilian Journal of Pharmaceutical Sciences, 2013
Medication errors can be frequent in hospitals; these errors are multidisciplinary and occur at various stages of the drug therapy. The present study evaluated the seriousness, the type and the drugs involved in medication errors reported at the Hospital
Gabriella Rejane dos Santos Dalmolin, Eloni Terezinha Rotta, José Roberto Goldim   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Medication errors in nursing students

فصلنامه پرستاری،مامایی و پیراپزشکی, 2018
Background & Aim: Internship nursing students are at risk of making medication errors due to their independence in practice. In order to protect the patient, identification of a drug error is necessary.
Zahra Khalili, Mehdi Molavi Vardanjani, Morteza Shamsizadeh, Neda Alimohammadi, Shahin Tohidi, Gholamhosein Fallahinia, Leili Tapak   +6 more
doaj  

A Model for Monitoring Spontaneously Reported Medication Errors Using the Adjuvanted Recombinant Zoster Vaccine as an Example

Advances in Pharmacological and Pharmaceutical Sciences
A European legislation was put in place for the reporting of medication errors, and guidelines were drafted to help stakeholders in the reporting, evaluation, and, ultimately, minimization of these errors. As part of pharmacovigilance reporting, a proper
Christophe Dessart, Fernanda Tavares-Da-Silva, Lionel Van Holle, Olivia Mahaux, Jens-Ulrich Stegmann   +4 more
doaj   +1 more source

Risk Factors, Causes, and Strategies for Reducing Medication Errors: A Narrative Review

مجلة علوم ذي قار
— Medication errors, which refer to any deviation from the prescribed medication regimen, can have seriously affected patient safety and treatment outcomes. It underscores the need for healthcare professionals to follow medication orders precisely and to
Suha Nadem, Makarim M. Ali Hassan, Amena Lafeta Muttlaq Al-Shareefi   +2 more
doaj   +1 more source

Lääkityspoikkeamista oppiminen [PDF]

, 2014
Tämän tutkimuksellisen kehittämistyön tarkoituksena oli analysoida lääkityspoikkeamien syitä ja etsiä yhdessä kuuden vanhustenhoidon yksikön henkilökunnan kanssa toteutettavia keinoja poikkeamien vähentämiseksi.
Valassaari, Satu
core  

Repeat prescribing of medications: a system-centred risk management model for primary care organisations [PDF]

, 2017
Rationale, aims and objectives: Reducing preventable harm from repeat medication prescriptions is a patient safety priority worldwide. In the United Kingdom, repeat prescriptions items issued has doubled in the last 20 years from 5.8 to 13.3 items ...
Bartlett, Stephen, Bowie, Paul, Dinwoodie, Mark, Man, Shu Ling, Price, Julie, Taylor, Kate   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source