Results 101 to 110 of about 178,986 (267)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Inter-rater reliability of medication error classification in a voluntary patient safety incident reporting system HaiPro in Finland

, 2018
Anna-Riia Holmström, Riina Järvinen, Raisa Laaksonen, Timo Keistinen, Persephone Doupi, Marja Airaksinen   +5 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Self-reported medical, medication and laboratory error in eight countries: risk factors for chronically ill adults [PDF]

, 2011
Antonia Scobie
openalex   +1 more source

Why is it so hard to reduce harm from medicines?

Future Healthcare Journal
Pharmacotherapy is the most common therapeutic intervention in healthcare, but more than 200 million medication errors occur every year in England alone.
Andrew Rochford
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Medication Errors: Will Punitive Measures Help to Decrease the Occurrence? A Case Study [PDF]

, 2013
Irene J. Su
openalex   +1 more source

IDENTIFICACIÓN Y ANÁLISIS DE LOS ERRORES DE MEDICACIÓN EN SEIS HOSPITALES BRASILEÑOS

Ciencia y Enfermería
Esta investigación identificó, a través del método de observación directa, los errores de medicación ocurridos en unidades de clínica médica de seis hospitales brasileños.
Silvia Helena de Bortoli Cassiani, Aline Aparecida Silvia Monzani, Ana Elisa Bauer De Camargo Silva, Flávio Trevisani Fakih, Simone Perufo Opitz, Thalyta Cardoso Alux Teixeira   +5 more
doaj   +1 more source

An urban medical system's exploratory study of medication errors [PDF]

, 2019
Skip Morelock, Jeffrey D. Kirk
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source