Results 61 to 70 of about 188,662 (265)

Apologies and Medical Error [PDF]

Clinical Orthopaedics & Related Research, 2009
One way in which physicians can respond to a medical error is to apologize. Apologies--statements that acknowledge an error and its consequences, take responsibility, and communicate regret for having caused harm--can decrease blame, decrease anger, increase trust, and improve relationships.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Medication errors in nursing students

فصلنامه پرستاری،مامایی و پیراپزشکی, 2018
Background & Aim: Internship nursing students are at risk of making medication errors due to their independence in practice. In order to protect the patient, identification of a drug error is necessary.
Zahra Khalili, Mehdi Molavi Vardanjani, Morteza Shamsizadeh, Neda Alimohammadi, Shahin Tohidi, Gholamhosein Fallahinia, Leili Tapak   +6 more
doaj  

Medication errors: classification of seriousness, type, and of medications involved in the reports from a university teaching hospital

Brazilian Journal of Pharmaceutical Sciences, 2013
Medication errors can be frequent in hospitals; these errors are multidisciplinary and occur at various stages of the drug therapy. The present study evaluated the seriousness, the type and the drugs involved in medication errors reported at the Hospital
Gabriella Rejane dos Santos Dalmolin, Eloni Terezinha Rotta, José Roberto Goldim   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Medication errors associated with carbapenems

Качественная клиническая практика, 2018
Purpose. The purpose of this study was to discover the prevalence and types of medication errors associated with the use of carbapenems. Materials and methods.
A. V. Kuz’mina, I. L. Asetskaya, V. A. Polivanov, S. K. Zyryanov   +3 more
doaj  

A Model for Monitoring Spontaneously Reported Medication Errors Using the Adjuvanted Recombinant Zoster Vaccine as an Example

Advances in Pharmacological and Pharmaceutical Sciences
A European legislation was put in place for the reporting of medication errors, and guidelines were drafted to help stakeholders in the reporting, evaluation, and, ultimately, minimization of these errors. As part of pharmacovigilance reporting, a proper
Christophe Dessart, Fernanda Tavares-Da-Silva, Lionel Van Holle, Olivia Mahaux, Jens-Ulrich Stegmann   +4 more
doaj   +1 more source

Risk Factors, Causes, and Strategies for Reducing Medication Errors: A Narrative Review

مجلة علوم ذي قار
— Medication errors, which refer to any deviation from the prescribed medication regimen, can have seriously affected patient safety and treatment outcomes. It underscores the need for healthcare professionals to follow medication orders precisely and to
Suha Nadem, Makarim M. Ali Hassan, Amena Lafeta Muttlaq Al-Shareefi   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source