Results 61 to 70 of about 388,903 (308)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Improving electronic medication reconciliation [PDF]
, 2011 Medication reconciliation is defined by the American Society of Health- System Pharmacists (ASHP) and the American Pharmacists Association (AphA) as “the comprehensive evaluation of a patient’s medication regimen any time there is a change in therapy in ...
Filiz, Esen
core
Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects during adolescence and cocaine abuse risk during adulthood [PDF]
, 2015 Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Baskin, Britahny M. +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
MEDICATION SYSTEM ANALYSIS OF AN UNIVERSITY HOSPITAL IN THE STATE OF GOIÁS [PDF]
Revista Eletrônica de Enfermagem, 2004 The medication errors can bring serious consequences to patients, professionals andhealthcare institutions, they have multiple causes, amongst them failures related to theprofessionals and related to the medication system.
Ana Elisa Bauer de Camargo Silva
doaj
Families, nurses and organisations contributing factors to medication administration error in paediatrics: a literature review [PDF]
, 2015 Background: Medication error is the most common adverse event for hospitalised children and can lead to significant harm. Despite decades of research and implementation of a number of initiatives, the error rates continue to rise, particularly those ...
Alomari, A +3 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Testing Nurses’ Medication Errors Model based on Reason Human Error Model
نشریه پرستاری ایران, 2013 Background & Aim: Medication errors are one of the most common medical errors. Since the performance of a theory in nursing is the extent of its application for description or prediction of evidence and also its potential in handling of the results as an
M Pazokian +3 more
doaj
The pattern of non-intercepted medication errors in a university affiliated teaching hospital [PDF]
, 2012 INTRODUCTION: The primary goal of reducing medication errors is to eliminate errors that reach the patient. We aimed to study the pattern of interception of medication errors along the medication use process.
Cheung, BMY +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source