Results 281 to 290 of about 2,458,624 (375)

Pharmacotherapy for Cirrhosis in Japan

Portal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

Patterns of Medication for Opioid Use Disorder During Pregnancy, 7 Clinical Sites, MATernaL and Infant clinical NetworK (MAT-LINK), 2014-2021. [PDF]

J Addict Med
Tran EL, Dorsey AN, Miele K, Gilboa SM, Gosdin L, Terplan M, Sanjuan PM, Seligman NS, Wright T, Wachman EM, Smid M, Henninger M, Leeman L, Schneider PD, Rood K, Louis JM, Caveglia S, Davidson A, Shakib J, Shrestha H, Meaney-Delman DM, Kim SY.   +21 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

The Odyssey of HOMER: Comparative Effectiveness Research on Medication for Opioid Use Disorder During the COVID-19 Pandemic. [PDF]

Ann Fam Med
Zittleman L, Westfall JM, Sofie B, Lutgen C, Fernald D, Hall TL, Hochheimer CJ, Murphy M, Felzien M, Dickinson LM, Manning BK, LeMaster J, Nease DE.   +12 more
europepmc   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

Small, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +1 more source

Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management

Small, EarlyView.
This review highlights the transformation of niclosamide, a repurposed drug, through molecular science strategies to overcome its pharmacokinetic limitations. Emphasizing novel nanohybrid technologies and delivery platforms, the article explores their therapeutic potential in targeting the complex pathophysiology of long COVID, paving the way for ...
Sanoj Rejinold N, Goeun Choi, Geun‐woo Jin, Jin‐Ho Choy   +3 more
wiley   +1 more source

Exploring the Lived Experiences of Medication for Opioid use Disorder Treatment: A Qualitative Study among a Crowdsourced Convenience Sample. [PDF]

Community Ment Health J
Victor G, Kheibari A, Strickland JC.
europepmc   +1 more source

Metabolic and addiction indices in patients on opioid agonist medication-assisted treatment: A comparison of buprenorphine and methadone [PDF]

, 2020
Albanese, Mark, Borodovsky, Jacob T., Borsook, David, Elman, Igor, Howard, Margaret, Mysels, David, Rott, David   +6 more
core   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Disorders of the gut‐brain interaction among European people with obesity: Prevalence and burden of compatible symptoms

United European Gastroenterology Journal, EarlyView.
Abstract Introduction The prevalence of disorders of the gut‐brain interaction (DGBI) among people with obesity in the general population is unknown. Our aim was to assess the prevalence of DGBI among obese subjects in the general population in comparison with normal or overweight subjects, as well as exploring factors associated with DGBI in obesity ...
Chloé Melchior, Jóhann P Hreinsson, Jan Tack, Jutta Keller, Qasim Aziz, Olafur S Palsson, Shrikant I Bangdiwala, Ami D Sperber, Magnus Simrén, Jean‐Marc Sabaté   +9 more
wiley   +1 more source