Results 71 to 80 of about 2,402,468 (250)

Multi-objective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex [PDF]

arXiv, 2023
Opioid Use Disorder (OUD) has emerged as a significant global public health issue, with complex multifaceted conditions. Due to the lack of effective treatment options for various conditions, there is a pressing need for the discovery of new medications. In this study, we propose a deep generative model that combines a stochastic differential equation (
arxiv  

Medicaid managed care restrictions on medications for the treatment of opioid use disorder

Health Services Research, Volume 60, Issue S2, April 2025.
Abstract Objective To examine whether Medicaid managed care plan (MCP) utilization management policies for buprenorphine–naloxone and injectable naltrexone are related to key state Medicaid program policy decisions. Data Sources and Study Setting We abstracted data on state Medicaid regulatory and policy information from publicly available sources and ...
Maureen T. Stewart, Christina M. Andrews, Sage R. Feltus, Dominic Hodgkin, Constance M. Horgan, Cindy Parks Thomas, Thuong Nong   +6 more
wiley   +1 more source

Identifying Risk of Opioid Use Disorder for Patients Taking Opioid Medications with Deep Learning [PDF]

arXiv, 2020
The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical interventions to reduce the risk of OUD.
arxiv  

Machine-learning Analysis of Opioid Use Disorder Informed by MOR, DOR, KOR, NOR and ZOR-Based Interactome Networks [PDF]

arXiv, 2023
Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved for OUD treatment, the efficacy of said agents for OUD requires further improvement in order to provide safer and ...
arxiv  

Characterizing and Identifying the Prevalence of Web-Based Misinformation Relating to Medication for Opioid Use Disorder: Machine Learning Approach

Journal of Medical Internet Research, 2021
BackgroundExpanding access to and use of medication for opioid use disorder (MOUD) is a key component of overdose prevention.
Mai ElSherief, Steven A Sumner, Christopher M Jones, Royal K Law, Akadia Kacha-Ochana, Lyna Shieber, LeShaundra Cordier, Kelly Holton, Munmun De Choudhury   +8 more
doaj   +1 more source

Preventing Infant Mortality Through Medicaid‐Administered Prenatal Care Coordination: Evidence From Wisconsin

Health Services Research, Volume 60, Issue S2, April 2025.
ABSTRACT Objective To estimate associations between Wisconsin Medicaid's Prenatal Care Coordination (PNCC) program and infant mortality. Data Sources and Study Setting We analyzed birth records, Medicaid claims, and infant death records for all resident and in‐state Medicaid‐paid live deliveries during 2010–2018.
David C. Mallinson, Yamikani B. Nkhoma‐Mussa, Kate H. Gillespie, Roger L. Brown   +3 more
wiley   +1 more source

Estimating the impact of stimulant use on initiation of buprenorphine and extended-release naltrexone in two clinical trials and real-world populations [PDF]

, 2023
BackgroundCo-use of stimulants and opioids is rapidly increasing. Randomized clinical trials (RCTs) have established the efficacy of medications for opioid use disorder (MOUD), but stimulant use may decrease the likelihood of initiating MOUD treatment ...
Arah, OA, Cook, RR, Foot, C, Humphreys, K, Korthuis, PT, Levander, XA, Luo, SX, Rudolph, KE, Tsui, JI   +8 more
core   +1 more source

Hospital-based clinicians lack knowledge and comfort in initiating medications for opioid use disorder: opportunities for training innovation

Addiction Science & Clinical Practice, 2023
Background Hospital-based clinicians infrequently initiate medications for opioid use disorder (MOUD) for hospitalized patients. Our objective was to understand hospital-based clinicians’ knowledge, comfort, attitudes, and motivations regarding MOUD ...
Andrea Jakubowski, Sumeet Singh-Tan, Kristine Torres-Lockhart, Shadi Nahvi, Melissa Stein, Aaron D. Fox, Tiffany Lu   +6 more
doaj   +1 more source

Racial, ethnic, and sex disparities in buprenorphine treatment from emergency departments by discharge diagnosis

Academic Emergency Medicine, EarlyView.
Abstract Objectives Racial and sex disparities are noted in the administration and prescribing of buprenorphine from emergency departments (EDs) nationally. It is unknown whether disparities persist when accounting for the specific discharge diagnosis addressed during encounters such as opioid overdose or withdrawal.
Neeraj Chhabra, Dale Smith, Natalie Parde, Nicole Hsing‐Smith, Joseph M. Bianco, R. Andrew Taylor, Gail D'Onofrio, Niranjan S. Karnik   +7 more
wiley   +1 more source

eDarkTrends: Harnessing Social Media Trends in Substance use disorders for Opioid Listings on Cryptomarket [PDF]

arXiv, 2021
Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being substance misuse causes poor mental health.
arxiv