Results 51 to 60 of about 15,511 (292)

Medication reconciliation – Responsibilities and barriers facing physicians, pharmacists, and nurses in Saudi Arabia

Saudi Journal for Health Sciences, 2022
Background: Patient safety can be adversely affected by medication errors. The medication reconciliation process plays a critical role in the prevention of medication discrepancies and adverse drug events.
Najah Saud Alanazi, Wafa A Alatawi, Kousalya Prabahar   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Design of MARQUIS2: study protocol for a mentored implementation study of an evidence-based toolkit to improve patient safety through medication reconciliation

BMC Health Services Research, 2019
Background The first Multi-center Medication Reconciliation Quality Improvement Study (MARQUIS1) demonstrated that implementation of a medication reconciliation best practices toolkit decreased total unintentional medication discrepancies in five ...
Amanda S. Mixon, G. Randy Smith, Meghan Mallouk, Harry Reyes Nieva, Sunil Kripalani, Stephanie Rennke, Eugene Chu, Anirudh Sridharan, Anuj Dalal, Stephanie Mueller, Mark Williams, Tosha Wetterneck, Jason M. Stein, Deonni Stolldorf, Eric Howell, John Orav, Stephanie Labonville, Brian Levin, Catherine Yoon, Marcus Gresham, Jenna Goldstein, Sara Platt, Christopher Nyenpan, Jeffrey L. Schnipper, the MARQUIS2 Site Leaders, the MARQUIS2 Study Group   +25 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Teaching Medication Reconciliation to Nursing Students Through Live Actor Simulation

, 2022
Medication reconciliation is a significantly important process for safe patient care. It is the process of creating an accurate list of medications that a patient takes.
Boll, Tamara
core   +1 more source

Brown Bag Simulation to Improve Medication Management in Older Adults

MedEdPORTAL, 2019
Introduction Medical students must care for aging patients with growing medication lists and need training to address negative patient outcomes associated with polypharmacy.
Chelsea E. Hawley, Laura K. Triantafylidis, Sarah C. Phillips, Andrea Wershof Schwartz   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effectiveness of pharmacist-led medication reconciliation on medication errors at hospital discharge and healthcare utilization in the next 30 days: a pragmatic clinical trial

Frontiers in Pharmacology
Transitions of care often lead to medication errors and unnecessary healthcare utilization. Medication reconciliation has been repeatedly shown to reduce this risk.
Maja Jošt, Maja Jošt, Mojca Kerec Kos, Mitja Kos, Lea Knez, Lea Knez   +5 more
doaj   +1 more source