ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
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Medication reconciliation in a hospital environment: Avoided discrepancies and cost savings - A single arm intervention study: Benefits of medication reconciliation in a hospital [PDF]
Medication reconciliation has proven to be essential for patient safety. However, studies on its economic viability are still scarce. Therefore, the aim of this study was to understand the avoided cost of medication discrepancies identified through the ...
Lays Cássia Santos Duarte +5 more
doaj +1 more source
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
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Prevalencia y caracterización de errores de medicación y conciliación en un hospital privado de segundo nivel en México | [Prevalence and characterization of medication and reconciliation errors in a second-level private hospital in Mexico] [PDF]
Context: Although progress has been made in recent decades in the knowledge and implementation of strategies and safe practices to prevent them, medication errors remain one of the main causes of avoidable harm in healthcare.
María I. Espinosa Sánchez +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Background: Medication reconciliation can include medication reviewing and providing counseling and a list of all the medications during every transition of care.
Melad Mohammed Ali, Ali Azeez Al-Jumaili
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Effect of therapeutic interchange on medication reconciliation during hospitalization and upon discharge in a geriatric population. [PDF]
Therapeutic interchange of a same class medication for an outpatient medication is a widespread practice during hospitalization in response to limited hospital formularies. However, therapeutic interchange may increase risk of medication errors.
Jessica S Wang +2 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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