Results 131 to 140 of about 4,247,513 (344)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

A Comparison of Incident Investigation Outcomes and Safety Recommendations between Clinical Safety and AcciMap Experts

open access: yes, 2022
This paper focuses on the perception of Branford’s standardized AcciMap approach as a tool for accident analysis in healthcare. This study further builds on the previous work regarding National Health Service (NHSScotland) clinical safety practitioners ...
Igene, Oseghale, Johnson, Christopher
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Reporting medication errors and near misses [PDF]

open access: yes, 2009
Introduction: Between January 2005 and June 2006 there were 59 802 medication safety incidents reported via the National Reporting and Learning System (NRLS) in England and Wales.
Williamson, Sheena
core  

Improving medication safety by cloud technology: Progression and value-added applications in Taiwan

open access: yesInt. J. Medical Informatics, 2019
OBJECTIVES To develop and implement an integrated cloud technology with the aim of ensuring medication reconciliation during transitions of care and improve medication safety in aged societies. METHODS PharmaCloud is a new technical platform adopted by
Chieh-Yu Liao   +7 more
semanticscholar   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Evaluation of factors contributing to medication errors among Nurses working at Mbagathi district hospital. [PDF]

open access: yes, 2015
Kenya healthcare policies provide that patient's dignity be observed by ensuring medical safety practices are observed. In this case, medication errors are a concern for both healthcare professionals as well as patients. The main aim of this study was to
Koech, Jane Jebet
core  

Medication safety problems priorities in community pharmacy in Saudi Arabia: a multi-stakeholder Delphi study using the human factors framework

open access: yesBMJ Open, 2019
Aim To achieve multi-stakeholder consensus and prioritisation of medication safety problems in community pharmacies in Saudi Arabia. Design and intervention A theoretically-underpinned, three-round Delphi study. Setting Saudi Arabia.
L. A. Al Juffali   +3 more
semanticscholar   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Predicting medication omission: a foundation for evidence-based strategies to improve patient safety.

open access: yes, 2011
OBJECTIVES The aim of this study was to identify the incidence and predictors (in terms of patient, system and drug related factors) of non-therapeutic medication omission amongst acutely ill medical and surgical adult patients; which relates to the ...
Latimer, Sharon
core   +1 more source

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