Results 51 to 60 of about 2,729,044 (237)

The use and safety risk of repurposed drugs for COVID-19 patients: lessons learned utilizing the Food and Drug Administration’s Adverse Event Reporting System

Saudi Pharmaceutical Journal, 2023
Objectives: This study was designed to assess the disproportionality analyses of adverse drug reactions (ADRs) related to hydroxychloroquine and remdesivir and how ADR reporting fluctuated during the COVID-19 pandemic.
Deemah S. Alsuhaibani, Heba H. Edrees, Thamir M Alshammari   +2 more
doaj   +1 more source

Safety of Compounded Medications

Cureus
Compounded medications are medications that are prepared by compounding pharmacies to meet individual patients' needs that cannot be met by FDA-approved brand name or generic medications. This may be the case when a patient needs a different dose or route of administration or if a patient is allergic to a certain ingredient in an FDA-approved ...
Garg, Rohini, Singh, Harmit
openaire   +2 more sources

Community Medication Safety Research

, 2022
The research aims to discover the social circumstances behind unsafe medication practices and avoidable medication-related harm using a community-based participatory research approach.
Helen McNamee, Caoimhe Shields
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Potentially inappropriate prescribing (PIP) in older people and its association with socioeconomic deprivation—a systematic review and narrative synthesis

BMC Geriatrics
Background Potentially inappropriate prescribing (PIP) refers to the prescription of medications that carry a higher risk of adverse outcomes, such as drug interactions, falls, and cognitive impairment.
Adrian James Hire, Bryony Dean Franklin
doaj   +1 more source

Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Open Chemistry, 2019
This study aimed to reveal potential roles of the phosphatidylinositol 3 kinase (PI3K)-protein kinase B (Akt)-mammalian target of rapamycin (mTOR) signaling pathway in apoptosis and autophagy of astrocytes induced by methamphetamine (METH).
Liu Han-Qing, An Ya-Wen, Hu A-Zhen, Li Ming-Hua, Wu Jue-Lian, Liu Li, Shi Yu, Cui Guang-Hui, Chen Yun   +8 more
doaj   +1 more source

The impact of implementing a hospital electronic prescribing and administration system on clinical pharmacists’ activities - a mixed methods study

BMC Health Services Research, 2019
Background The increasing adoption of hospital electronic prescribing and medication administration (ePA) systems has driven a wealth of research around the impact on patient safety.
Monsey McLeod, Georgios Dimitrios Karampatakis, Lore Heyligen, Ann McGinley, Bryony Dean Franklin   +4 more
doaj   +1 more source

Association of medication storage with diabetes control: A cross-sectional study from Saudi Arabia

Saudi Pharmaceutical Journal, 2020
Background: In addition to diet restriction and physical activity, diabetes mellitus is managed by the chronic use of medications that require appropriate storage conditions to maintain their stability and effectiveness.
Ali F. Altebainawi, Mubarak N. Alrashidi, Moaath K. Aljbreen, Muhammad Majid Aziz, Abdullah A. Alhifany, Mohamad Aljofan, Thamir M. Alshammari   +6 more
doaj   +1 more source

Are countries’ precautionary actions against COVID-19 effective? An assessment study of 175 countries worldwide

Saudi Pharmaceutical Journal, 2021
Background: The coronavirus disease 2019 (COVID-19) pandemic has affected many countries negatively, particularly in terms of their health care and financial systems. Numerous countries have attempted to employ precautions to address this pandemic.
Thamir M. Alshammari, Khalidah A. Alenzi, Fatemah A. Alnofal, Ghada Fradees, Ali F. Altebainawi   +4 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source