Results 101 to 110 of about 426,276 (300)

Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions

, 2006
Background. Assessing illness perceptions has been useful in a range of medical disorders. This study of people with a recent relapse of their psychosis examines the relationship between illness perception, their emotional responses and their attitudes ...
Garety, PA, Bebbington, P E, P. W. B. Watson, Freeman, D, Weinman, J, Weinman, J., Fowler, D., Dunn, G., Dunn, G, Bebbington, PE, D. Fowler, J. Weinman, G. Dunn, Garety, P A; id_orcid, Kuipers, E; id_orcid, Watson, PWB, Watson, PW, Fowler, D, Kuipers, E, Watson, P W B, E. Kuipers, Watson, P. W. B., Freeman, D., Bebbington, P. E., Freeman, Daniel, P. E. Bebbington, D. Freeman, P. A. Garety, Garety, P. A., Kuipers, E.   +29 more
core   +1 more source

Patient reported outcomes in view of symptom experience of late effects and self-management of adult long-term survivors after allogeneic haematopoietic stem cell transplantation - a mixed methods study [PDF]

, 2014
Even years after allogeneic stem cell transplantation, recipients face a continuing risk of developing serious late effects. Previous studies have focused on the pathophysiological understanding of late effects, as well as on treatment and disease ...
Kirsch, Monika
core   +1 more source

Positioning a Paediatric Compounded Non-Sterile Product Electronic Repository (pCNPeRx) within the Health Information Technology Infrastructure

Pharmacy, 2015
Numerous gaps in the current medication use system impede complete transmission of electronically identifiable and standardized extemporaneous formulations as well as a uniform approach to medication therapy management (MTM) for paediatric patients.
Richard H. Parrish, II
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Psychological treatments in schizophrenia: I. Meta-analysis of family intervention and cognitive behaviour therapy

, 2002
Background. While there is a growing body of evidence on the efficacy of psychological interventions for schizophrenia, this meta-analysis improves upon previous systematic and meta-analytical reviews by including a wider range of randomized controlled ...
Pilling, S., Geddes, J., Morgan, C, Geddes, J, Kuipers, E, Bebbington, P., Garety, P, Morgan, C., Orbach, G., Garety, P., Bebbington, P, Garety, P; id_orcid, Pilling, S, Orbach, G, Kuipers, E; id_orcid, Kuipers, E.   +15 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Factors Influencing Adherence to Antiretroviral Treatment in Nepal: A Mixed-Methods Study [PDF]

, 2012
Background Antiretroviral therapy (ART) is a lifesaver for individual patients treated for Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS).
Freeman, Janifer, van Teijlingen Edwin, Freeman, Jennifer, Jennifer V Freeman, van Teijlingen, E., Randall Julian, Sharada P Wasti, Randall, Julian, Edwin van Teijlingen, Simkhada Padam, Simkhada, Padam, Simkhada, P., Julian Randall, Padam Simkhada, Wasti, S.P., Randall, J., Freeman Jennifer V., Wasti, Sharada Prasad, van Teijlingen, Edwin, Wasti Sharada P., Rabdal, Julian, Freeman, J.V.   +21 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Medication Therapy Management and Preconception Care: Opportunities for Pharmacist Intervention [PDF]

, 2014
As medication therapy management (MTM) continues to grow in the profession of pharmacy, careful consideration as to areas for positive patient impact is warranted.
Bright, David R., Natalie A. DiPietro, DiPietro, Natalie A., Di Pietro, Natalie A., David R. Bright   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source