Results 91 to 100 of about 60,441 (347)

Overcoming barriers to traditional care delivery and pharmacy challenges: a qualitative study of buprenorphine, telehealth, and a digital therapeutic for opioid use disorder

Substance Abuse Treatment, Prevention, and Policy
Background The opioid epidemic contributes to increasing morbidity and mortality due to drug overdoses in the US, but barriers to traditional opioid use disorder (OUD) treatment prevent a vast majority of patients from accessing quality care and ...
Laura B. Monico, Megan Eastlick, Darcy Michero, Peyton Pielsticker, Suzette Glasner   +4 more
doaj   +1 more source

An Exploratory Study of Suboxone (Buprenorphine/ Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability [PDF]

, 2019
Suboxone films are U.S. Food and Drug Administration approved to treat opioid dependence. While the package insert states that films should not be cut, physicians often prescribe film fractions for treatment and tapering. There is no data to support this
Conn, Kelly, Corigliano, Anthony, DeAngelis, Michael J., Ferrara, Alexander S., Phillips, Elizabeth, Reindel, Kristin L., Zhao, Fang   +6 more
core   +1 more source

Single high-dose buprenorphine for opioid craving during withdrawal. [PDF]

, 2018
BackgroundOpioid use disorder is one of the most prevalent addiction problems worldwide. Buprenorphine is used as a medication to treat this disorder, but in countries where buprenorphine is unavailable in combination with naloxone, diversion can be a ...
Ahmadi, Jamshid, Ghahremani, Dara, Jahromi, Mina Sefidfard, London, Edythe D   +3 more
core   +2 more sources

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098 an open-label randomized comparative effectiveness trial of extended-release buprenorphine versus treatment as usual on post-hospital treatment engagement for hospitalized patients with opioid use disorder

Addiction Science & Clinical Practice
Background Hospitalizations involving opioid use disorder (OUD) are increasing. Addiction consultation services (ACS) initiate medications for opioid use disorder (MOUD) in hospital settings and arrange post-hospital follow-up for ongoing MOUD care ...
Gavin Bart, Kelly S. Barth, Paulette Baukol, Eva Enns, Udi E. Ghitza, Jacklyn Harris, Eve Jelstrom, Jane M. Liebschutz, Kara M. Magane, Delia Voronca, Zoe M. Weinstein, P. Todd Korthuis   +11 more
doaj   +1 more source

Knowledge, experiences, and perceptions of medications for opioid use disorder among Black Kentuckians

Annals of Medicine
Background Opioid overdoses have continued to increase at higher rates among Black Americans compared to people from other racial groups. Despite demonstrated effectiveness of MOUD in reducing risk of opioid overdose, Black Americans face decreased ...
Paris B. Wheeler, Brittany Miller-Roenigk, Jasmine Jester, Danelle Stevens-Watkins   +3 more
doaj   +1 more source

GWAS-identified genetic variants associated with medication-assisted treatment outcomes in patients with opioid use disorder: a systematic review and meta-analysis protocol [PDF]

, 2020
Caroul Chawar, Alannah Hillmer, Stephanie Sanger, Alessia D’Elia, Balpreet Panesar, Lucy Guan, Dave Xiaofei Xie, Nandini Bansal, Aamna Abdullah, Flávio Kapczinski, Guillaume Paré, Lehana Thabane, Zainab Samaan   +12 more
openalex   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Exemplar Hospital initiation trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098B a randomized implementation study to support hospitals in caring for patients with opioid use disorder

Addiction Science & Clinical Practice
Background Hospitalizations involving opioid use disorder (OUD) are increasing. Medications for opioid use disorder (MOUD) reduce mortality and acute care utilization.
Gavin Bart, P. Todd Korthuis, Julie M. Donohue, Hildi J. Hagedorn, Dave H. Gustafson, Angela R. Bazzi, Eva Enns, Jennifer McNeely, Udi E. Ghitza, Kara M. Magane, Paulette Baukol, Ashley Vena, Jacklyn Harris, Delia Voronca, Richard Saitz   +14 more
doaj   +1 more source

Impact of recent methamphetamine use on treatment outcomes among individuals initiating medications for opioid use disorders in rural treatment settings: a 1-year retrospective cohort study

Rural and Remote Health
Introduction: Rates of N-methylamphetamine (methamphetamine) use in rural areas of the US have been steadily increasing, particularly among individuals who are already struggling with opioid use disorder.
Leslie Kenefick, Lisa Khairy, Luke Hall, Kibeom Kwon, Nicole Limberg, Kirsi Kirk-Lewis, Megan Lewis, Matt Owen, Sterling McPherson, Andre Miguel   +9 more
doaj   +1 more source