Results 61 to 70 of about 60,441 (347)

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

A primary care, multi-disciplinary disease management program for opioid-treated patients with chronic non-cancer pain and a high burden of psychiatric comorbidity [PDF]

, 2005
BACKGROUND: Chronic non-cancer pain is a common problem that is often accompanied by psychiatric comorbidity and disability. The effectiveness of a multi-disciplinary pain management program was tested in a 3 month before and after trial.
A Rosenblum, AK Burton, AM Elliott, B McCarberg, B Meier, C Maier, CA Hammett-Stabler, CA Soderstrom, CD DeAngelis, CS Cleeland, CS Cleland, CS Cleland, D Bloodsworth, D Fujimoto, DA Fishbain, DA Regier, Darren A DeWalt, DC Turk, DC Turk, DE Joranson, DE Joranson, DE Moulin, DE Weissman, DG Rischitelli, DJ Kavanagh, H Flor, H Ghodse, H McQuay, J Gardner-Nix, J Porter, J Stephen Perhac, JD Bartleson, JD Clark, JE Veney, JK Iglehart, JM Harris Jr, JM Romano, JT Chibnall, JT Farrar, Katherine M Felix, KB Wells, L Allan, L Peters, L Radloff, L Webb, LH Pengel, LK Mannix, M van Tulder, Mary E Bryant, MC Reid, MC Rowbotham, ME Geisser, MF Ballesteros, MI Donovan, Michael P Pignone, MJ Bair, MJ Bair, NG Hoffmann, NJ Adams, OxyContin®, P Belluck, PA Hill, Paul R Chelminski, PE Greenberg, R Colvin, R Friedman, R Melzack, R Rothman, RA Deyo, RB Lipton, RB Lipton, RC Tait, RH Fletcher, RK Portenoy, RK Portenoy, RK Portenoy, RN Jamison, RN Jamison, Robert M Malone, RS Epstein, SA Dunbar, SD Passik, SG Gelfand, SH Roth, SM Fishman, SR Savage, SR Ytterberg, Steven D Prakken, T Bodenheimer, T Bodenheimer, T Bodenheimer, Thomas M Miller, Timothy J Ives, W Arkinstall, WF Stewart, Y Olsen   +95 more
core   +4 more sources

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

Advanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park, Hak‐Young Ahn, Minho Seong, Taehoon Kim, Yulin Zhou, Yameng Xu, Jaehee Lee, Ritika Raj Menghani, Yujin Choi, Minsu Park, Nadir Muzaffar, Youngeun Lee, Seung Gi Seo, Jong Uk Kim, Sang Min Won, Jahyun Koo, Elena Aprea, Taeyeon Kim, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, Raudel Avila, Geumbee Lee, John A. Rogers   +23 more
wiley   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R, Jahangir, A Alex, Miller, Anna N, Mir, Hassan R, Obremskey, William T   +4 more
core   +1 more source

Individual and county-level factors associated with use of multiple prescribers and multiple pharmacies to obtain opioid prescriptions in California. [PDF]

, 2012
Use of multiple prescribers and pharmacies is a means by which some individuals misuse opioids. Community characteristics may be important determinants of the likelihood of this phenomenon independent of individual-level factors. This was a retrospective
Han, Huijun, Kass, Philip, Li, Chin-Shang, Wilsey, Barth   +3 more
core   +2 more sources

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021

JAMA Network Open, 2023
This cross-sectional study uses data from the 2021 National Survey on Drug Use and Health to estimate the receipt of medication for opioid use disorder among US adults with past-year opioid use disorder.
Jones, Christopher M., Han, Beth, Baldwin, Grant T., Einstein, Emily B., Compton, Wilson M.   +4 more
openaire   +2 more sources

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Opioid Addiction 2016 Facts & Figures [PDF]

, 2016
National Opioid Overdose Epidemic* Drug overdose is the leading cause of accidental death in the US, with 55,403 lethal drug overdoses in 2015. Opioid addiction is driving this epidemic, with 20,101 overdose deaths related to prescription pain relievers,

core  

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source