Results 61 to 70 of about 35,888 (296)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Naltrexone implant for opioid use disorder. [PDF]

, 2021
The continued rise in the availability of illicit opioids and opioid-related deaths in the United States has left physicians, researchers, and lawmakers desperate for solutions to this ongoing epidemic.
Orellana, Claudia V, Amber N. Edinoff, Cornett, Elyse M., Bulloch, Blaine T, Crane, Erin A., Kaye, Adam M., Alan D. Kaye, Nix, Catherine A, Elyse M. Cornett, Rachel L. Kozinn, Stpierre, Samantha M., Bulloch, Blaine T., Kevin S. Murnane, Claudia V. Orellana, Cornett, Elyse M, Adam M. Kaye, Kozinn, Rachel L, Erin A. Crane, Murnane, Kevin S, Murnane, Kevin S., Blaine T. Bulloch, Kozinn, Rachel L., Catherine A. Nix, Kaye, Adam M, Kaye, Alan David, Nix, Catherine A., Samantha M. StPierre, Edinoff, Amber N, StPierre, Samantha M, Crane, Erin A, Kaye, Alan D, Orellana, Claudia V.   +31 more
core   +2 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Targeting the Orexin System for Prescription Opioid Use Disorder [PDF]

, 2020
Prescription opioids are potent analgesics that are used for clinical pain management. However, the nonmedical use of these medications has emerged as a major concern because of dramatic increases in abuse and overdose. Therefore, effective strategies to
Rémi Martin-Fardon, Alessandra Matzeu
core   +1 more source

The Relationship between Dissociative Symptoms and the Medications Used in the Treatment of Opioid Use Disorder [PDF]

, 2021
Opioid use disorder has long been associated with psychiatric symptoms, including dissociative experiences. Medications used to treat opioid use disorder can potentially impact dissociative symptoms, but the existing literature has not explored this.
Crawford, Timothy, Wright, Mark D., Gainer, Danielle, Fischer, Karley B.   +3 more
core   +1 more source

Community-Centered Patient Journey Map in Opioid Use Disorder: A Tool to Address Compassion Fatigue among Community Pharmacists

Pharmacy, 2023
Community pharmacists have become increasingly exposed to opioid use disorders in recent decades. However, both pharmacist training and traditional practice environments have not been adequate to prepare the pharmacist for both the patient care needs and
Kenneth Charles Hohmeier, Alina Cernasev, Christina Leibold, Todd M. Moore, Erica Schlesinger, Gerald Cochran, Ileana Arce, Wesley Geminn, Marie Chisholm-Burns   +8 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

Impact of continuing care on recovery from substance use disorder. [PDF]

, 2021
Continuing care is widely believed to be an important component of effective treatment for substance use disorder, particularly for those individuals with greater problem severity.
McKay, James R
core   +1 more source

Rapid Access to Medications for Opioid Use Disorder [PDF]

Journal of General Internal Medicine, 2021
Robert A. Kleinman, Nathaniel P. Morris
openaire   +2 more sources