Results 51 to 60 of about 1,809,699 (361)

A novel and alternative in vitro method using microwave to study the epithelial-stromal interactions [PDF]

open access: yes, 2009
The goal of the present work was to obtain a simple and reproducible experimental model that would maintain the characteristics of the extracellular physiological environment of breast epithelial cells, both in factors as well as stromal structure, on ...
Calvo, Juan Carlos   +3 more
core  

Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]

open access: yes, 2017
Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Aya Castañeda, Maria del Rosario   +6 more
core   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

Botánica médica de los indígenas Cuna de Arquía, Chocó

open access: yesCaldasia, 1995
A medical-botanical study in the indigenous Cuna community of Arquia (Choco) with the collaboration of the Inatuledi (botanical doctor) Claudio Izquierdo is presented. Different aspects about health, illness and the healing process are discussed.
Giraldo Tafur Clara
doaj  

Médicos e farmacêuticos em Uberabinha (1890-1920): conflitos e disputas Physicians and pharmacists in Uberabinha (1890-1920): conflicts and disputes

open access: yesHistória, Ciências, Saúde: Manguinhos, 2007
Apresenta alguns resultados do estudo sobre as práticas de médicos e farmacêuticos na cidade de São Pedro de Uberabinha (MG), hoje Uberlândia, durante as décadas de 1890 e 1920.
Antônio de Pádua Bosi
doaj   +1 more source

Cooperation in the iterated prisoner's dilemma is learned by operant conditioning mechanisms [PDF]

open access: yes, 2004
The prisoner's dilemma (PD) is the leading metaphor for the evolution of cooperative behavior in populations of selfish agents. Although cooperation in the iterated prisoner's dilemma (IPD) has been studied for over twenty years, most of this research ...
Gutnisky, D. A.   +1 more
core   +1 more source

Subventricular Zone‐on‐a‐Chip: A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

open access: yesAdvanced Science, EarlyView.
A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni   +6 more
wiley   +1 more source

A Colônia enferma e a saúde dos povos: a medicina das 'luzes' e as informações sobre as enfermidades da América portuguesa The ailing colony and the health of the people: the medicine of the Enlightenment and information about the infirmities in Portugal's American colonies

open access: yesHistória, Ciências, Saúde: Manguinhos, 2007
Os avanços da medicina no conhecimento do corpo humano e nas formas de tratar as enfermidades não tiveram impacto somente sobre o corpo individual. A partir do século das luzes a medicina passou a se preocupar cada vez mais com a 'saúde dos povos'.
Jean Luiz Neves Abreu
doaj   +1 more source

Allogeneic mesenchymal stromal cells overexpressing mutant human Hypoxia-inducible factor 1-α (HIF1-α) in an ovine model of acute myocardial infarction [PDF]

open access: yes, 2016
Background-Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors.
Crottogini, Alberto José   +11 more
core   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim   +9 more
wiley   +1 more source

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