Results 51 to 60 of about 1,830,846 (361)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Allogeneic mesenchymal stromal cells overexpressing mutant human Hypoxia-inducible factor 1-α (HIF1-α) in an ovine model of acute myocardial infarction [PDF]

open access: yes, 2016
Background-Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors.
Crottogini, Alberto José   +11 more
core   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

Botánica médica de los indígenas Cuna de Arquía, Chocó

open access: yesCaldasia, 1995
A medical-botanical study in the indigenous Cuna community of Arquia (Choco) with the collaboration of the Inatuledi (botanical doctor) Claudio Izquierdo is presented. Different aspects about health, illness and the healing process are discussed.
Giraldo Tafur Clara
doaj  

Médicos e farmacêuticos em Uberabinha (1890-1920): conflitos e disputas Physicians and pharmacists in Uberabinha (1890-1920): conflicts and disputes

open access: yesHistória, Ciências, Saúde: Manguinhos, 2007
Apresenta alguns resultados do estudo sobre as práticas de médicos e farmacêuticos na cidade de São Pedro de Uberabinha (MG), hoje Uberlândia, durante as décadas de 1890 e 1920.
Antônio de Pádua Bosi
doaj   +1 more source

Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]

open access: yes, 2016
Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra   +10 more
core   +2 more sources

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim   +9 more
wiley   +1 more source

A Colônia enferma e a saúde dos povos: a medicina das 'luzes' e as informações sobre as enfermidades da América portuguesa The ailing colony and the health of the people: the medicine of the Enlightenment and information about the infirmities in Portugal's American colonies

open access: yesHistória, Ciências, Saúde: Manguinhos, 2007
Os avanços da medicina no conhecimento do corpo humano e nas formas de tratar as enfermidades não tiveram impacto somente sobre o corpo individual. A partir do século das luzes a medicina passou a se preocupar cada vez mais com a 'saúde dos povos'.
Jean Luiz Neves Abreu
doaj   +1 more source

The natural history of nonalcoholic fatty liver disease: mortality rates and liver enzymes [PDF]

open access: yes, 2017
Nonalcoholic fatty liver disease (NAFLD) has emerged as an important health issue of the modern world, due to the dramatic increase in its prevalence, which has doubled and in some regions tripled in the past decade.
Pirola, Carlos José   +1 more
core   +1 more source

Expanding the Genotype–Phenotype Correlation of Marden–Walker Syndrome due to PIEZO2 Gene Variants: A Case Report From Brazil

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marden–Walker syndrome (MWS; OMIM 248700) is an extremely rare congenital disorder characterized by multiple joint contractures, craniofacial dysmorphism, neurological abnormalities, and multisystem involvement. Although historically diagnosed on clinical grounds, only a few cases have been molecularly confirmed.
Guilherme Sotto Battiston   +35 more
wiley   +1 more source

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