Results 61 to 70 of about 1,752,513 (362)

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

open access: yesArthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead   +4 more
wiley   +1 more source

Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism [PDF]

open access: yes, 2016
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis.
Abruzzese, Giselle Adriana   +6 more
core   +2 more sources

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

Quetelet, el hombre medio y el saber médico

open access: yesHistória, Ciências, Saúde: Manguinhos, 2013
Analizo, a partir de dos libros de Adolphe Quetelet, su teoría del 'hombre medio' o que permite asociar la normalidad biológica y social a la frecuencia de aparición de determinadas características poblacionales.
Sandra Caponi
doaj   +1 more source

A novel and alternative in vitro method using microwave to study the epithelial-stromal interactions [PDF]

open access: yes, 2009
The goal of the present work was to obtain a simple and reproducible experimental model that would maintain the characteristics of the extracellular physiological environment of breast epithelial cells, both in factors as well as stromal structure, on ...
Calvo, Juan Carlos   +3 more
core  

As origens da Medicina: a Medicina no Antigo Egito

open access: yesRevista de História, 1962
A Humanidade, desde os tempos pré-históricos, vinha se preocupando, e muito, com o problema de como enfrentar a morte, derrotar a doença e conseguir evitar que esta se implantasse no organismo humano. 
openaire   +5 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

The natural history of nonalcoholic fatty liver disease: mortality rates and liver enzymes [PDF]

open access: yes, 2017
Nonalcoholic fatty liver disease (NAFLD) has emerged as an important health issue of the modern world, due to the dramatic increase in its prevalence, which has doubled and in some regions tripled in the past decade.
Pirola, Carlos José   +1 more
core   +1 more source

Subventricular Zone‐on‐a‐Chip: A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

open access: yesAdvanced Science, EarlyView.
A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni   +6 more
wiley   +1 more source

The clinical method as a learning content in the medicine career.

open access: yesMedisur, 2010
The clinical method constitutes an important content in the learning process of the medical career. This article is aimed at reviewing the most essential aspects related to the topic in order to contribute to the deepening on this knowledge among ...
Luis Alberto Corona Martínez
doaj  

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