Results 11 to 20 of about 9,005 (233)

Pensar la medicina amb la història [PDF]

open access: yes, 2023
The history of medicine has undergone a major transformation in recent decades. Professor María José Báguena Cervellera (1956-2021) has been a witness and protagonist of these changes throughout more than forty years of full dedication to the history of ...
Ferragud, Carmel   +1 more
core   +7 more sources

Les biografies mèdiques : entre l'hagiografia i la història [PDF]

open access: yes, 2004
Taula rodona "Noves tendències historiogràfiques de la medicina a les portes del segle XXI"El treball analitza la tradició del gènere biogràfic dins la historiografia mèdica, iniciada amb el model biobibliogràfic i continuada amb les grans figures de la ...
Congrés d'Història de la Medicina Catalana (13è : 2004 : La Canonja, Catalunya)   +5 more
core   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Problematic Internet Use in Frontotemporal Dementia: A Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso   +9 more
wiley   +1 more source

Da neurastenia ao estresse: notas para uma história das doenças nervosas

open access: yesRevista de História, 2023
O texto trata de alguns aspectos da história da neurastenia e do advento do estresse, incluindo suas relações com o imaginário das doenças nervosas, entre o final do século XIX e as primeiras décadas do século XX.
Denise Bernuzzi de Sant´Anna
doaj  

Sacralizar el acto médico. Valores éticos y profesionales entre medicina y farmacia, Colombia, 1894-1914

open access: yesHistoria y Memoria, 2021
En Colombia, la historia de la profesionalización es un problema poco explorado. La historia social de las ciencias y la sociología de las profesiones nos aportan una base para interrogarla.
Jorge Márquez Valderrama   +1 more
doaj   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

os Entornos Innovadores de Aprendizaje como respuesta a los retos educativos del siglo XXI

open access: yesResearch in Education and Learning Innovation Archives
El presente artículo realiza una reflexión sobre la oportunidad que suponen los Entornos Innovadores de Aprendizaje para hacer frente a los retos del siglo XXI.
Amelia Rosa Granda Piñán   +1 more
doaj   +1 more source

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