Results 31 to 40 of about 9,005 (233)
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
Advanced Materials Technologies, EarlyView.This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Historia Mexicana El Colegio de México, 2007 Por medio de la correspondencia que entre 1937-1957 sostuvieron los historiadores Henry Sigerist y José Joaquín Izquierdo, el trabajo pretende hacer una interpretación del devenir de la historia de la medicina.
Gabriela Castañeda López +1 more
doaj
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Advanced Science, EarlyView.SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
Batallas contra la lepra: estado, medicina y ciencia en Colombia
Anuario Colombiano de Historia Social y de la Cultura, 2002 Diana Obregón Torres. Batallas contra la lepra: Estado, medicina y ciencia en Colombia, Medellín: Banco de la República / EAFIT, 2002, pp. 436. La historia de las ciencias y de la medicina en Colombia tiene sus orígenes en dos obras que aparecen en el ...
Néstor Miranda Canal
doaj +2 more sources
Josep Miquel Vidal Hernández [Miquel Àngel Casasnovas Camps. ed.] Enciclopèdia de Menorca. Tom tretzè. Història de la Medicina I. Maó: Fundació Enciclopèdia de Menorca; 2017 [PDF]
, 2020 Obra ressenyada: Josep Miquel VIDAL HERNÁNDEZ, Miquel Àngel CASASNOVAS CAMPS (ed.), Enciclopèdia de Menorca. Tom tretzè. Història de la Medicina I.
Sallent del Colombo, Emma
core
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
La historiografia de la malaltia durant el segle XX [PDF]
, 2004 Fins a ben endins la dècada de 1920 la idea de que les malalties són entitats naturals essencialment contínues en l'espai i el temps -i, com a màxim, susceptibles en el cas de les afeccions infeccioses, d'experimentar canvis explicables per les lleis ...
Arrizabalaga, Jon +2 more
core +1 more source
História, Ciências, Saúde: Manguinhos, 2007 O Instituto Brasileiro de História da Medicina foi fundado em 1945 pelo médico Ivolino de Vasconcellos. Como pretendia ter caráter nacional, foi criada também a Federação Nacional de História da Medicina e Ciências Afins. Esse grupo possuía uma concepção
Mauro Amoroso
doaj +1 more source
Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis
Annals of Neurology, EarlyView.Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi +33 more
wiley +1 more source