Results 51 to 60 of about 19,137 (183)

SCN9A should not be considered an epilepsy gene; Refuting a gene–disease association

open access: yesEpilepsia, Volume 66, Issue 9, Page 3516-3527, September 2025.
Abstract Objective The SCN9A gene is primarily expressed in nociceptive pathways within the peripheral nervous system, and pathogenic variants are associated with human pain disorders. In recent years, several studies have proposed SCN9A as a monogenic cause of epilepsy.
Ismael Ghanty   +7 more
wiley   +1 more source

Expression of long non‐coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple‐negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell death

open access: yesMolecular Oncology, 2019
Triple negative breast cancer (TNBC) represents an aggressive phenotype with poor prognosis compared with ER, PR, and HER2‐positive tumors. TNBC is a heterogeneous disease, and gene expression analysis has identified seven molecular subtypes ...
Fredy Omar Beltrán‐Anaya   +15 more
doaj   +1 more source

Programación fetal de enfermedades expresadas en la etapa adulta [PDF]

open access: yes, 2008
Este estudio revisa algunos factores intrauterinos implicados en el desarrollo del individuo durante la vida fetal y neonatal dando lugar al concepto de “programación fetal” y expresión de enfermedades en la etapa adulta.
Martínez de Villarreal, Laura Elia
core  

Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID‐19

open access: yesJournal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT The coronavirus disease 2019 (COVID‐19) pandemic has triggered a global health crisis, with over 700 million confirmed cases and at least 7 million deaths reported by early 2024. Children are less vulnerable to severe SARS‐CoV‐2 infection than adults and typically experience milder respiratory symptoms.
Alysson Henrique Urbanski   +43 more
wiley   +1 more source

Tendencias actuales de la investigación genómica. Sus perspectivas en Nicaragua. [PDF]

open access: yes, 2009
El contenido del artículo se enfoca en las tendencias y el impacto de las nuevas ciencias moleculares, cuyas revelaciones están transformando el mundo e incluso heredándonos una nueva cosmovisión. A continuación, se consideran las posibilidades de que un
Huete-Pérez, Jorge Alberto
core  

Use of Human Umbilical Vein Endothelial Cells (HUVEC) as a Model to Study Cardiovascular Disease: A Review

open access: yesApplied Sciences, 2020
Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive research has been performed to understand this disease better, using various experimental models. The endothelium plays a crucial role in the development of CVD, since it
Diana J. Medina-Leyte   +4 more
doaj   +1 more source

José María Ordovás, investido doctor honoris causa por la Universidad de Córdoba [PDF]

open access: yes, 2008
Nota de prensa elaborada por el Gabinete de Comunicación sobre el nombramiento de José María Ordovás como Doctor Honoris Causa por la Universidad de ...
Gabinete de Comunicación. UCO
core  

La medicina centrada en las personas y la medicina personalizada

open access: yesMedisur, 2015
En los últimos años, ante la avalancha tecnológica y de especialización, se ha introducido el concepto de medicina centrada en las personas, que enfatiza en la atención individual de los enfermos como sujetos, con un enfoque holístico, general, no ...
Alfredo Darío Espinosa Brito
doaj   +2 more sources

Enhanced PDMS Functionalization for Organ‐on‐a‐Chip Platforms Using Ozone and Sulfo‐SANPAH: A Simple Approach for Biomimetic Long‐Term Cell Cultures

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 13, May 16, 2025.
The use of organ‐on‐a‐chip (OOC) microfluidic platforms is expanding in biomedical research. While this emerging technology is becoming increasingly accessible, the stability of long‐term functional cultures remains a critical challenge to address. This study presents a straightforward, one‐step method for the functionalization of polydimethylsiloxane ...
Mitzi Pérez‐Calixto   +7 more
wiley   +1 more source

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster

open access: yesJournal of Applied Toxicology, Volume 45, Issue 5, Page 841-857, May 2025.
ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy