Results 51 to 60 of about 10,915 (266)

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, EarlyView.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

LINFOMA EXTRANODAL NK/T CELL NASAL: RELATO DE CASO CLÍNICO

Hematology, Transfusion and Cell Therapy
Introdução: O linfoma extranodal NK/T-cell tipo nasal é doença agressiva de células T periférico, associado ao vírus Epstein Barr (EBV), com prognóstico ruim e sobrevida média de 2a.
LGF Lima, MFH Costa, ASA Silva, TR Evangelista, ACC Lopes, JO Vieira, MC Araujo, HC Moura, EMS Thorpe, GSD Cortez   +9 more
doaj   +1 more source

Individual Cognitive Remediation Therapy and Individual Emotion Skills Training for Anorexia Nervosa: A Case Series Study in a Paediatric Ward

European Eating Disorders Review, EarlyView.
ABSTRACT Introduction Adolescents with anorexia nervosa (AN) often present cognitive rigidity, impaired decision‐making, and difficulties processing emotions, all of which can impede engagement in treatment. The marked rise in paediatric hospitalisations for AN during the COVID‐19 pandemic highlights the urgent need for brief, targeted interventions in
Dario Marin, Federica Tedde, Federico Muzzarelli, Paola Elisa Cogo, Lucia Giombini   +4 more
wiley   +1 more source

Surgical outcomes of a low-cost adapted sacrospinous fixation for apical prolapse repair

Revista de Enfermagem da UFPI
Objective: To assess surgical outcomes of women submitted to the adapted sacrospinous fixation (SSF) at a school hospital in northeastern Brazil for apical prolapse repair.
Francilberto Souza, Artur Eduardo de Oliveira Rangel, Alex Sandro Rolland Souza, Aurélio Antônio Ribeiro Costa   +3 more
doaj   +1 more source

Selective episiotomy vs. implementation of a non-episiotomy protocol: a randomized clinical trial

Reproductive Health, 2017
Background Despite all the evidence corroborating the selective use of episiotomy and although routine use of the procedure is contraindicated, there are no evidences corroborating if episiotomy is necessary in any circumstance.
M. M. Amorim, Isabela Cristina Coutinho, Inês Melo, Leila Katz   +3 more
doaj   +1 more source

Maternal and perinatal outcomes in women with and without hypertensive syndromes submitted to induction of labor with misoprostol

Hypertension in Pregnancy, 2017
Objectives: To determine maternal and perinatal outcomes according to the mode of delivery in normotensive and hypertensive women bearing a live, full-term fetus, who were submitted to labor induction with misoprostol. Methods: Retrospective cohort study.
Rossana Mariana Carvalho de Paiva Marques, Alex Sandro Rolland Souza, Francisco Edson de Lucena Feitosa, Aurélio Antônio Ribeiro da Costa, Melania Maria Ramos Amorim   +4 more
doaj   +1 more source

Effectiveness of an action-oriented educational intervention in ensuring long term improvement of knowledge, attitudes and practices of community health workers in maternal and infant health: a randomized controlled study

BMC Medical Education, 2018
Background The potential role of Community Health Workers (CHWs) in improving maternal and child health outcomes, particularly in low and middle-income countries and in disadvantaged communities, is receiving increased attention.
Tereza Rebecca de Melo e Lima, Paula Ferdinanda Conceição de Mascena Diniz Maia, Emanuelle Pessa Valente, Francesca Vezzini, Giorgio Tamburlini   +4 more
doaj   +1 more source

Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification

International Journal of Cancer, EarlyView.
What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez, Carla Debernardi, Alessandra Allione, Elton Jalis Herman, Simonetta Guarrera, Daniela Ferrante, Anna Aspesi, Marika Sculco, Marta La Vecchia, Carlotta Sacerdote, Federica Grosso, Christina M. Lill, Giovanna Masala, Marcela Guevara, Matthias B. Schulze, Salvatore Panico, Yaszan Asgari, Seehyun Park, Giovanna Tagliabue, Anne Tjønneland, Antonio Agudo, Elisabete Weiderpass, Corrado Magnani, Irma Dianzani, Paolo Vineis, Elisabetta Casalone, Giuseppe Matullo   +26 more
wiley   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source