Results 61 to 70 of about 22,519 (209)

Pharmacological manipulation of the immediate effects of spinal trauma in neonatal rats reveals a crucial role for TRPV4 receptors

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi   +5 more
wiley   +1 more source

Radiofármacos en medicina nuclear

open access: yes, 2015
Un radiofármaco es un compuesto radiactivo utilizado para el diagnóstico y tratamiento de enfermedades. En Argentina, el 95% de los radiofármacos utilizados en medicina nuclear son de diagnóstico mientras que aproximadamente un 5% de usan para terapia.
Chain, Cecilia Yamil, Illanes, Luis
openaire   +3 more sources

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman‐Diamond syndrome‐associated mutation

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez   +6 more
wiley   +1 more source

Understanding cell‐penetrating peptide mechanisms using computational electrophysiology simulations

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Cell‐penetrating peptides (CPPs) can enter cells without inducing cytotoxicity and can be coupled with cargo molecules to be used to deliver drugs, DNA, or nanoparticles into cells. The peptide‐membrane interactions driving the internalization mechanism are not completely understood. In this study, we introduce Computational Electrophysiology (
Eric Catalina‐Hernandez   +3 more
wiley   +1 more source

Trazabilidad de las mediciones realizadas con activímetros en medicina nuclear

open access: yesNucleus, 2008
En medicina nuclear, las dosis del radiofármaco administradas se expresan mediante la actividad del radionucleido en el preparado. La medición de esa actividad se realiza en el activímetro y resulta primordial para garantizar la comparabilidad nacional e
Pilar Oropesa Verdecia   +2 more
doaj  

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Nuclear Medicine in the Covid-19 pandemic. [PDF]

open access: yesRev Esp Med Nucl Imagen Mol (Engl Ed), 2020
Conesa JC.
europepmc   +1 more source

Can Peer Victimization Invalidate the Positive Effect of Emotional Intelligence on Adolescents' Health‐Related Quality of Life?

open access: yesJournal of School Health, Volume 96, Issue 4, April 2026.
ABSTRACT Background Emotional intelligence (EI) is a key factor in adolescents' health‐related quality of life (HRQoL). Previous research has shown that higher EI is associated with better HRQoL outcomes. However, its protective role may be weakened by adverse experiences such as peer victimization.
Ángela de Lourdes MARTÍN‐PÉREZ   +1 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, Volume 16, Issue 3, Page 461-473, March 2026.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

MEDICINA NUCLEAR: APLICACION EN PATOLOGIA OSTEOARTICULAR

open access: yesRevista Chilena de Radiología
La mayor parte del área osteoarticular en medicina nuclear, tiene como principal examen la cintigrafía ósea, ya sea planar o con técnica SPECT (single photon emision computed tomography). Existen algunos otros exámenes usados como el estudio con Galio-67,
Pamela Humeres A
doaj   +1 more source

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