Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Acaricidal efficacy of medicinal plants against <i>Rhipicephalus</i> (<i>Boophilus</i>) <i>microplus</i> in Africa: A systematic review. [PDF]
Tawana M +7 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Regulatory approach to manipulated organs in Europe: preserving human organs as non-commercial goods. [PDF]
Cuende N, Izeta A, Domínguez-Gil B.
europepmc +1 more source
Disaster Medicine — Humanitarian Medicine [PDF]
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Use of medicinal herbs in an Iranian population: cross-sectional findings from the Fasa PERSIAN Cohort Study. [PDF]
Mosavat SH +9 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
En las comunidades Las Peñas y Las Piñas de Julcuy se realizó una investigación etnobiológica, sustentada en los vacíos sobre información referente a los componentes de la diversidad utilizados por los habitantes de las comunidades rurales.
René Gras Rodríguez +3 more
doaj
Severe Climate-Driven Range Contraction of <i>Taverniera abyssinica</i> A. Rich, an Endangered and Locally Popular Medicinal Plant in Ethiopia. [PDF]
Birhanu L +4 more
europepmc +1 more source

