Results 161 to 170 of about 126,087 (296)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Implementation of the Three Rs in the Human Hazard Assessment of Brazilian Medicinal Plants: An Evaluation of the Cytotoxic and Genotoxic Potentials of Dipteryx alata Vogel

, 2011
In Brazil, medicinal plants are widely used by the indigenous people, which leads to a constant requirement for toxicity tests to be performed on the plant extracts.
Rodas, Andrea C. D., Dal Belo, Chariston A., Santos, Marcio G. dos, Oshima-Franco, Yoko, Lopes, Patricia Santos [UNIFESP], Esteves-Pedro, Natalia M.   +5 more
core  

Could non-humans have Traditional Ecological Knowledge? And if so, what should we do about it? [PDF]

J Ethnobiol Ethnomed
Freymann E, Schultz F, Redfearn D.
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

The Tupinambá of Maranhão State, Brazil, and medicinal plants described in the 17th century chronicles of the Capuchins Claude d'Abbeville and Yves d'Évreux. [PDF]

J Ethnobiol Ethnomed
Gomes WC, Linhares JFP, Medeiros MFT.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Protocol for a Scoping Review of the Evidence for the Medicinal Use of Natural Honey and/or its Derivatives in Animals

, 2019
In this scoping review, our broad research question is: "What is the nature and extent of the current body of evidence addressing the medicinal use of natural honey and/or its derivatives in animals?
Sargeant, Jan, Vogt, Nadine, Julien, Danielle   +2 more
core  

Laboratory Animal Medicine [PDF]

Journal of Medical Genetics, 1985
  +5 more sources

Learning from animals? shared plant use between Lua herders and water buffalo in Northern Thailand. [PDF]

J Ethnobiol Ethnomed
Lainé N, Fooyontphanich K, Janyasuthiwong S, Prommanut P.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source