Results 181 to 190 of about 397,906 (291)

Fucoidan in cancer therapy: from biomedical application to medicinal chemistry approach. [PDF]

J Mater Sci Mater Med
Zheng Y, Fang S, Liu N, Zhang T, Huang Y, Li L, Tian Y, Hu X, Ji Y, Guo Y, Tu Y.   +10 more
europepmc   +1 more source

Natural Products Chemistry, Medicinal Resources [PDF]

, 2005
Suresh Awale, 手塚 康弘, 門田 重利   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Medicinal chemistry [PDF]

, 2019
openaire   +2 more sources

Ugi and Groebke-Blackburn-Bienaymé Reactions in Medicinal Chemistry: An Outlook on New Bioactive Compounds. [PDF]

ACS Omega
Barbosa-Reis G, Lavorenti J, Alves BL, Oliveira-Silva D.   +3 more
europepmc   +1 more source

Bio-organic and Medicinal Chemistry [PDF]

, 2008
竹内 義雄, 藤原 朋也
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Building a Medicinal Chemistry Framework for Bioorthogonal Probes. [PDF]

ACS Cent Sci
Staudt M, Carlson JCT.
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Lipophilic Cations as Mitochondria-Targeting Moieties: Recent Progress and Design Principles for Medicinal Chemistry. [PDF]

J Med Chem
Džajić I, Tomašič T, Pardo LA, Peterlin Mašič L, Cotman AE.   +4 more
europepmc   +1 more source