Results 111 to 120 of about 126,235 (359)

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj   +6 more
wiley   +1 more source

THE USE OF THE MEDICINAL HERBS IN THE CITY OF VELENJE

open access: yesZdravniški Vestnik, 2004
Background. Data about the use of medicinal herbs for selftreatment in our population is sparse. Therefore the aim of our survey was to investigate the measures taken by patients with four most frequent symptoms, which medicinal herbs they used and where
Zalika Klemenc Ketiš, Franc Verovnik
doaj  

N-butylphthalide (NBP) and ligustrazine (TMP) triazole hybrids target the KEAP1-NRF2 pathway to inhibit ferroptosis and exert brain neuroprotectivity

open access: yesRedox Biology
Ischemic stroke is a life-threatening disease, its pathological progression involves multiple factors, including oxidative stress, apoptosis, and ferroptosis. Our previous study demonstrated that hybridizing N-butylphthalide (NBP) with ligustrazine (TMP)
Guangyu Li   +9 more
doaj   +1 more source

Effects of phosphorus-solubilizing fungi on bulb quality and the Fritillaria taipaiensis rhizosphere soil environment [PDF]

open access: yesPeerJ
Background Fritillaria taipaiensis P.Y. Li is commonly used in Chinese medicine for its cough-suppressing and expectorant properties. Due to over-excavation and ecological damage, the wild resources of F.
Xueyang Ren   +6 more
doaj   +2 more sources

Analysis of black holes in our knowledge concerning animal health in the organic food production chain [PDF]

open access: yes, 2003
Although a large body of research on health aspects can be found via the web or in conference proceedings, only few papers reach the peer reviewed literature.
Eijck, Ineke   +4 more
core  

Capability Development in the European Medicines Regulatory Network—A European Learning Needs Analysis and Survey Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The European Medicines Regulatory Network plays a critical role in safeguarding public health through the assessment and supervision of human medicines. However, rapid scientific and technological advancements have exposed capability deficits across the network, threatening timely and effective regulatory decision‐making.
Naomi Beard   +4 more
wiley   +1 more source

Simulation of the Metabolism of New Psychoactive Substances Using Electrochemistry‐Mass Spectrometry: Introducing an Innovative Software Tool for Rapid Data Evaluation

open access: yesDrug Testing and Analysis, EarlyView.
A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner   +3 more
wiley   +1 more source

Medicinal plants used as indigenous herbs for anti-helminthic activity of North-Eastern region of India [PDF]

open access: bronze, 2023
Prodipto Roy   +5 more
openalex   +1 more source

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