Results 41 to 50 of about 9,668 (285)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The medicinal use of leeches in Malta [PDF]
, 2002 The medical practice based on the Greek doctrine of the four humors considered that disease was due to alterations in the composition of these humors, and therapy was therefore based on attempting to restore the balance.
Savona-Ventura, Charles +2 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Journal of Vector Borne DiseasesBackground & objectives: Amphotericin B, Allopurinol, Glucantime and Beta-Glucan are the main drugs currently used for the treatment of cutaneous leishmaniasis.
Leila Shirani-Bidabadi
doaj +1 more source
Leech as a lifeboat: Reminiscent role in plastic and reconstructive surgery!
TNOA Journal of Ophthalmic Science and Research, 2019 Leeching was a popular therapeutic practice since ancient times for various diseases. Previously, it was used as an unscientific home remedy by traditional therapists.
Rohan Dilip Newadkar +1 more
doaj +1 more source
Pharmacological Or Genetic Targeting Of Transient Receptor Potential (TRP) Channels Can Disrupt The Planarian Escape Response [PDF]
, 2019 In response to noxious stimuli, planarians cease their typical ciliary gliding and exhibit an oscillatory type of locomotion called scrunching. We have previously characterized the biomechanics of scrunching and shown that it is induced by specific ...
Cochet-Escartin, O. +5 more
core +4 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Scanning behavior in the medicinal leech Hirudo verbana. [PDF]
PLoS ONE, 2014 While moving through their environment, medicinal leeches stop periodically and wave their head or body back and forth. This activity has been previously described as two separate behaviors: one called 'head movement' and another called 'body waving ...
Cynthia M Harley, Daniel A Wagenaar
doaj +1 more source
Frontiers in Pediatrics, 2023 BackgroundAcute limb ischemia due to microvascular malperfusion may be refractory to initial therapies. Medicinal leech therapy (hirudotherapy) has been attempted in plastic and reconstructive surgery to improve venous congestion in ischemic flaps ...
Joseph C. Resch +4 more
doaj +1 more source
A kinematic and computational study of leech crawling: Support for a CPG based on travelling waves of excitation. [PDF]
, 2000 Many well characterized central pattern generators (CPGs) underlie behaviors (e.g., swimming, flight, heartbeat) that require regular rhythmicity and strict phase relationships.
Cacciatore, TW, Rozenshteyn, R, W, B
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