Results 41 to 50 of about 2,490 (244)

Hirudotherapy for limb ischemia in the pediatric intensive care unit: A retrospective observational cohort

Frontiers in Pediatrics, 2023
BackgroundAcute limb ischemia due to microvascular malperfusion may be refractory to initial therapies. Medicinal leech therapy (hirudotherapy) has been attempted in plastic and reconstructive surgery to improve venous congestion in ischemic flaps ...
Joseph C. Resch, Rachel Hedstrom, Marie E. Steiner, Sameh M. Said, Arif Somani   +4 more
doaj   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis

Journal of Neuroinflammation, 2012
Background In invertebrates, the medicinal leech is considered to be an interesting and appropriate model to study neuroimmune mechanisms. Indeed, this non-vertebrate animal can restore normal function of its central nervous system (CNS) after injury ...
Tahtouh Muriel, Garçon-Bocquet Annelise, Croq Françoise, Vizioli Jacopo, Sautière Pierre-Eric, Van Camp Christelle, Salzet Michel, Nagnan-le Meillour Patricia, Pestel Joël, Lefebvre Christophe   +9 more
doaj   +1 more source

Ingestive Behaviour and Physiology of the Medicinal Leech [PDF]

Journal of Experimental Biology, 1988
ABSTRACT Ingestion lasts 25 min in Hirudo medicinalis and is characterized by pharyngeal peristalsis which fills the crop. This peristalsis has an initial rate of 2·4 Hz which decays smoothly to 1·2 Hz at termination of ingestion. During ingestion, the leech body wall undergoes peristalsis which appears to aid in filling the crop ...
C M, Lent, K H, Fliegner, E, Freedman, M H, Dickinson   +3 more
openaire   +2 more sources

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews, Bruce Goodwin, Lauren Buckley, Rick Walker   +3 more
wiley   +1 more source

Excisional Wound Morphological Characteristics Under the Influence of Medicinal Leech Biologically Active Substances

Innovative Biosystems and Bioengineering
Background. The stages of wound healing following surgery are generally consistent, but immune responses and increased inflammation can delay the normal healing process. As a result, additional support is crucial.
Ruslan Aminov, Alina Aminova
doaj   +1 more source

Emotional component of pain perception in the medicinal leech?

Animal Sentience, 2022
Crump et al. have provided a series of criteria to assess animal sentience that is focused on the perception of pain, which is known to have both sensory and emotional components. They also provide a qualitative scoring system to assess data that address
Brian D Burrell
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Hirudotherapy /Leech therapy: Applications and Indications in Surgery

Archives of Clinical and Experimental Surgery, 2012
Hirudotherapy (HT) is the application of medicinal leeches (Hirudo medicinalis) for therapeutic use. It is one of the oldest remedies, being employed by various medicinal practitioners.
Swaid Abdullah, Latief M. Dar, Adil Rashid, Anita Tewari   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source