Results 71 to 80 of about 4,166,177 (341)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Journal of Medicinal Plants, 2014 Glycyrrhiza glabra (Licorice) is a perennial shrub belongs to the Fabaceae family. It is widely used in food pharmaceutical products and tobacco industry because of its important secondary metabolites.
M Khanahmadi +6 more
doaj
Evaluation of Phytochemical and Biochemical Patterns of Lemon Verbena (Lippia citriodora H.B.K.) at Different Temperatures [PDF]
Research Journal of Pharmacognosy, 2019 Background and objectives: Lemon verbena (Lippia citriodora H.B.K.) from Verbenaceae family, as an aromatic and medicinal plant, has attracted interests for its valuable essential oil (EO).
Hanieh Rafiee +4 more
doaj +1 more source
Approaches to Decrease Hyperglycemia by Targeting Impaired Hepatic Glucose Homeostasis Using Medicinal Plants [PDF]
, 2021 Gerardo Mata-Torres +2 more
openalex +1 more source
Journal of Ethnobiology and Ethnomedicine, 2020 Background People’s classification, management, and use of plants represent attempt to attracting people from different academic disciplines. Many countries use traditional medicine for their primary healthcare system.
Zewdie Kassa +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Antidiabetic Potential of Medicinal Plants and Their Active Components
Biomolecules, 2019 Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health.
B. Salehi +23 more
semanticscholar +1 more source
Antimicrobial Importance of Medicinal Plants in Nigeria
TheScientificWorldJournal, 2020 Despite the success of antibiotic discovery, infectious diseases remain the second leading source of death worldwide, while the resistance to antibiotics is among the significant problems in the twenty-first century.
H. Ugboko +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Allometric Ratio of Menthol and Menthone to Pulegone in the Essential Oil of Peppermint (Mentha piperita L.) Affected by Bioregulators [PDF]
Research Journal of Pharmacognosy, 2018 Background and objectives: Menthol and menthone are two important components in the essential oil of peppermint(Mentha piperita L.) which are commercially used in the pharmaceutical industries. This study has presented the allometric ratio of menthol and
Meisam Pourhadi +4 more
doaj +1 more source