Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Habitat Conditions of the Most Important Medicinal Plants from Lamiaceae Family in Mazandaran Province [PDF]
The production and proper utilization of medicinal plants in natural habitats need to review and identify the natural conditions and climate of the habitat of these plants and separating them from harmful and poisonous plants. The current study was aimed
Ehsan Zandi Esfahan +2 more
core +1 more source
Does the taste matter? Taste and medicinal perceptions associated with five selected herbal drugs among three ethnic groups in West Yorkshire, Northern England [PDF]
YesIn recent years, diverse scholars have addressed the issue of the chemosensory perceptions associated with traditional medicines, nevertheless there is still a distinct lack of studies grounded in the social sciences and conducted from a cross ...
Andrea Pieroni +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Application of Medicinal Plants in Poultry Nutrition [PDF]
Application of most antibiotic growth promoters as feed additives has been banned in a lot of countries due to cross-resistance against pathogens and residues in tissues.
core +1 more source
Traditionally Used Medicinal Plants of Armenia [PDF]
The rich and diverse flora of Armenia has been used for medicinal purposes for at least 3000 years. The relevant literature in Armenian, English, and Russian revealed a vast array of used medicinal plants, some of them unique to the Caucasus region.
Zidorn, Christian +3 more
core +1 more source
Relative antioxidant activity of Brazilian medicinal plants for gastrointestinal diseases
The free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay.
Kitagawa, Rodrigo R. +5 more
core +3 more sources
Introduction: Chitosan is one of the polysaccharides containing nitrogen which is synthesized naturally by deacetylation reaction of chitin and is confirmed as one of the efficient biostimulants for improvement of secondary metabolites production in ...
M Mehregan +3 more
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