Results 1 to 10 of about 1,196 (180)

Evaluation of the Transfer and Occurrence of Opium Alkaloids in Poppy Seed Teas Using Preconcentrations with µSPEed^® Followed by GC-MS Analysis

Chemosensors, 2023
Intoxication due to the consumption of poppy seed teas has been reported due to their contamination with opium alkaloids (OAs). In this work, an efficient methodology based on microsolid-phase extraction (µSPEed®) followed by gas chromatography–mass ...
Gema Casado-Hidalgo, Rosa Perestelo, Sonia Morante-Zarcero, José S. Câmara, Isabel Sierra   +4 more
doaj   +1 more source

THEBAINE METABOLITES IN THE URINE OF RHESUS MONKEYS

Japanese Journal of Pharmacology, 1981
The metabolic fate of thebaine in rhesus monkeys was investigated. Using thin layer chromatography, more than four metabolites were detected in the urine of monkeys given thebaine (8 mg/kg, s.c.). Two of the metabolites isolated by high performance liquid chromatography were not consistent with those reported previously.
YAMAZOE, Yasushi, NUMATA, Hiroaki, YANAGITA, Tomoji   +2 more
openaire   +2 more sources

A Systematic Review on Main Chemical Constituents of Papaver bracteatum

Journal of Medicinal Plants, 2015
Papaver bracteatum Lindly (Papaveraceae) is an endemic species of Iran which has economic importance in drug industries. The main alkaloid of the plant is thebaine which is used as a precursor of the semi-synthetic and synthetic compounds including ...
M Soleymankhani, F Khalighi-Sigaroodi, R Hajiaghaee, H Naghdi Badi, A Mehrafarin, M Ghorbani Nohooji   +5 more
doaj  

Endophytic Consortium With Diverse Gene-Regulating Capabilities of Benzylisoquinoline Alkaloids Biosynthetic Pathway Can Enhance Endogenous Morphine Biosynthesis in Papaver somniferum

Frontiers in Microbiology, 2019
Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray, Shiv S. Pandey, Alok Pandey, Madhumita Srivastava, Karuna Shanker, Alok Kalra   +5 more
doaj   +1 more source

Optimization of Thebaine Production using Adventitious Roots of Papaver bracteatum Lindle. by Alteration of Aeration Volume and Temperature in Bioreactor

Journal of Medicinal Plants, 2019
Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami, H Naghdi Badi, A Qaderi, A Mehrafarin, F Khalighi-Sigaroodi, AR Zare Karizi   +5 more
doaj  

High variations of the thebaine concentrations in Iranian poppy (Papaver bracteatum Lindl.) from various regions in Iran

Journal of Applied Botany and Food Quality
This paper aims to contribute reliable information to promote the pharmacological utilization of Papaver bracteatum by analyzing its wild population in Iran. For this purpose, 27 Iranian poppy specimens from 7 provinces of Iran were analyzed.
Mahdi Yahyazadeh, Mahshid Rahimifard, Najmeh Hadi, Zahra Shirazi, Samaneh Asadi-sanam, Razieh Azimi, Yousef Ajani, Maryam Makizadeh, Aiuob Moradi, Mahmood Bidarlord, Mozhgan Larti, Hamideh Fakhr-ranjbari, Negar Valizadeh, Taiebeh Amini, Dirk Selmar   +14 more
doaj   +1 more source

Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli

Nature Communications, 2016
Opiates—the gold standard for pain relief—are currently produced by extraction from opium poppies. Here the authors show that bacteria can serve as an efficient and flexible platform for the production of opiates by demonstrating the total synthesis of ...
Akira Nakagawa, Eitaro Matsumura, Takashi Koyanagi, Takane Katayama, Noriaki Kawano, Kayo Yoshimatsu, Kenji Yamamoto, Hidehiko Kumagai, Fumihiko Sato, Hiromichi Minami   +9 more
doaj   +1 more source

In Vitro Polyploidy Induction in Persian Poppy (Papaver bracteatum Lindl.)

Caryologia, 2020
Papaver bracteatum Lindl. grows as a wild perennial medicinal plant in Northern Iran and is known mainly for its high amounts of the pharmaceutically valuable alkaloid of thebaine. In vitro production of tetraploid P.
Saeed Tarkesh Esfahani, Ghasem Karimzadeh, Mohammad Reza Naghavi   +2 more
doaj   +1 more source

The Effect of L-tyrosine on Thebaine Production in Cell Suspension Culture of Iranian Poppy (Papaver bracteatum)

Journal of Medicinal Plants, 2016
Background: Using of elicitors and different compounds in cell suspension culture is an effective strategy for enhancement and improvement of important secondary metabolites production in in vitro conditions.
R Farjaminezhad, N Zare, R Asghari-Zakaria, M Farjaminezhad   +3 more
doaj  

Improved evaluation method for reliable distinction of poppy (Papaver somniferum L.) cultivars

International Journal of Horticultural Science, 1999
Investigating seven Hungarian standard cultivars (i.e. 'A1’, 'Kék Gemona', '13C-2`,'Kék Duna', `Kompolti M’, `Gödi N', 'Kozmosz) it was proved that for the reliable distinction between cultivars a complex analysis is necessitated. Because of the large
J. Bernáth, J. Bakó, F. Petheő
doaj   +1 more source