Results 1 to 10 of about 3,283 (227)

Bioinformatics deciphers the thebaine biosynthesis pathway in opium poppy: Hub genes, network analysis, and miRNA regulation [PDF]

Journal of Genetic Engineering and Biotechnology
Thebaine, a vital precursor in the codeine and morphine pathway, shows promise in addiction treatment. We conducted a comprehensive study on the thebaine biosynthesis pathway in opium poppy, utilizing bioinformatics tools.
Zahra Shirazi, Mahsa Rostami, Abozar Ghorbani, Pietro Hiram Guzzi   +3 more
doaj   +2 more sources

Salutaridine and its derivatives as thebaine-equivalents in the synthesis of aporphines [PDF]

Open Chemistry, 2013
Here we report on the transformation of tetracyclic morphinan salutaridine (1) into 2,3,10,11-tetrasubstituted (R)-aporphines. This method serves as another chemical proof of the previously verified biosynthetic connection with pentacyclic ...
Udvardy Antal, Sipos Attila
doaj   +2 more sources

Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability and biotransformation yield [PDF]

Journal of Biological Engineering
The cultivation of opium poppy is the only commercially viable source of most morphinan alkaloids. Bioproduction of morphinan alkaloids in recombinant whole-cell systems provides a promising alternate source of these valuable compounds.
Garrick W. K. Spencer, Xu Li, Kenny W. L. Lam, George Mutch, Fiona H. Fry, Sally L. Gras   +5 more
doaj   +2 more sources

Chemiluminescence determination of pethidine hydrochloride and thebaine alkaloides [PDF]

شیمی کاربردی روز, 2023
The aim of this work was finding new flurescent dyes as sensitizers for chemiluminescence (CL) determination some of narcotics. In this way 6 different dyes incloding rhodamine 6G, brilliant blue, orange G, chromatrope, eosin‌‌Y and [Ru(phen)3]2+ and 14 ...
Massoud Karimi, Ali Mokhtari, Aliakbar Dehno Khalaji   +2 more
doaj   +1 more source

Investigation of the acid/base behaviour of the opium alkaloid thebaine in LC-ESI-MS mobile phase by NMR spectroscopy [PDF]

Royal Society Open Science, 2017
As part of a research programme to establish an analytical method for the simultaneous detection of the five major opium alkaloids in poppy seeds by liquid chromatography–electrospray ionization–mass spectrometry (LC-ESI-MS) it was discovered that the ...
Michelle G. Carlin, John R. Dean, Jonathan L. Bookham, Justin J. B. Perry   +3 more
doaj   +1 more source

Investigation of Alkaloids in Opium Poppy (Papaver somniferum L.) Varieties and Hybrids

Journal of Agricultural Sciences, 2021
This study aimed to investigate the proportions of morphine, thebaine, noscapine, codeine, oripavine and papaverine alkaloids in poppy varieties and hybrids. Nine parents and 36 hybrid lines were used in the trial.
Levent Yazici, Güngör Yılmaz
doaj   +1 more source

Evaluation of Thermal Degradation of Tropane and Opium Alkaloids in Gluten-Free Corn Breadsticks Samples Contaminated with Stramonium Seeds and Baked with Poppy Seeds under Different Conditions

Foods, 2022
In this work, the thermal degradation of tropane and opium alkaloids was studied in samples of breadsticks prepared with corn flour, contaminated with seeds of Datura stramonium, and containing seeds of Papaver somniferum L.
Fernando L. Vera-Baquero, Sonia Morante-Zarcero, Isabel Sierra   +2 more
doaj   +1 more source

Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]

, 2011
The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena, Dharmendra Kumar Yadav, Feroz Khan, Rakesh K. Shukla, Sema Singh, Sonal Mishra   +5 more
core   +2 more sources

Opium Alkaloids in Harvested and Thermally Processed Poppy Seeds

Frontiers in Chemistry, 2020
The opium alkaloids (morphine, codeine, thebaine, noscapine, and papaverine) have been detected on poppy seeds; they are widely used by the food industry for decoration and flavor but can introduce opium alkaloids into the food chain.
Michelle G. Carlin, John R. Dean, Jennifer M. Ames   +2 more
doaj   +1 more source

Un édifice au nom du roi Héqataoui (Ahmosé Ier) dans la nécropole thébaine [PDF]

Polish Archaeology in the Mediterranean, 2021
While there is massive evidence of the mortuary cult of Ahmose I’s family at Abydos, in the form of pyramids, cult buildings and texts, the Theban necropolis is virtually devoid of archaeological testimony on the building activities of the founder of the
Frédéric Colin
doaj   +1 more source