Results 41 to 50 of about 1,919 (204)
Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.In the realm of cardiovascular diseases, myocardial ischemia–reperfusion injury (MIRI) is known as one of the main life‐threatening conditions with significant morbidity and mortality. Although some therapeutic approaches, like pharmacological treatments and ischemic preconditioning, have been suggested for MIRI, offering a functional approach with ...
Mehdi Dehghani Firoozabadi +3 more
wiley +1 more source
Papaver bracteatum Lindley: thebaine content in relation to plant development
, 1977 Four thebaine-rich varieties of P. bracteatum have been grown in the open over two seasons and the thebaine distribution in aerial parts examined to determine the most suitable source material for commercial production. The leaves contained only 0·1 to 0·
K Helliwell, J W Fairbairn
core +1 more source
A Systematic Review on Main Chemical Constituents of Papaver bracteatum
Journal of Medicinal Plants, 2015 Papaver bracteatum Lindly (Papaveraceae) is an endemic species of Iran which has economic importance in drug industries. The main alkaloid of the plant is thebaine which is used as a precursor of the semi-synthetic and synthetic compounds including ...
M Soleymankhani +5 more
doaj
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Nature Communications, 2016 Opiates—the gold standard for pain relief—are currently produced by extraction from opium poppies. Here the authors show that bacteria can serve as an efficient and flexible platform for the production of opiates by demonstrating the total synthesis of ...
Akira Nakagawa +9 more
doaj +1 more source
Frontiers in Microbiology, 2019 Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray +5 more
doaj +1 more source
Journal of Medicinal Plants, 2016 Background: Using of elicitors and different compounds in cell suspension culture is an effective strategy for enhancement and improvement of important secondary metabolites production in in vitro conditions.
R Farjaminezhad +3 more
doaj
In Vitro Polyploidy Induction in Persian Poppy (Papaver bracteatum Lindl.)
Caryologia, 2020 Papaver bracteatum Lindl. grows as a wild perennial medicinal plant in Northern Iran and is known mainly for its high amounts of the pharmaceutically valuable alkaloid of thebaine. In vitro production of tetraploid P.
Saeed Tarkesh Esfahani +2 more
doaj +1 more source
THEBAINE METABOLITES IN THE URINE OF RHESUS MONKEYS
Japanese Journal of Pharmacology, 1981 The metabolic fate of thebaine in rhesus monkeys was investigated. Using thin layer chromatography, more than four metabolites were detected in the urine of monkeys given thebaine (8 mg/kg, s.c.). Two of the metabolites isolated by high performance liquid chromatography were not consistent with those reported previously.
YAMAZOE, Yasushi +2 more
openaire +2 more sources
Yeast, Volume 42, Issue 12, Page 303-310, December 2025.ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley +1 more source
Journal of Medicinal Plants, 2019 Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami +5 more
doaj