Results 41 to 50 of about 1,660 (216)
Frontiers in Microbiology, 2019 Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray +5 more
doaj +1 more source
ChemCatChem, Volume 17, Issue 21, November 10, 2025.Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen +4 more
wiley +1 more source
Direct and Simple O-Demethylation of Thebaine to Oripavine
, 2016 Direct and Simple O-Demethylation of Thebaine to ...
Andrew Coop (1416964) +2 more
core +1 more source
Journal of Medicinal Plants, 2016 Background: Using of elicitors and different compounds in cell suspension culture is an effective strategy for enhancement and improvement of important secondary metabolites production in in vitro conditions.
R Farjaminezhad +3 more
doaj
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Nature Communications, 2016 Opiates—the gold standard for pain relief—are currently produced by extraction from opium poppies. Here the authors show that bacteria can serve as an efficient and flexible platform for the production of opiates by demonstrating the total synthesis of ...
Akira Nakagawa +9 more
doaj +1 more source
In Vitro Polyploidy Induction in Persian Poppy (Papaver bracteatum Lindl.)
Caryologia, 2020 Papaver bracteatum Lindl. grows as a wild perennial medicinal plant in Northern Iran and is known mainly for its high amounts of the pharmaceutically valuable alkaloid of thebaine. In vitro production of tetraploid P.
Saeed Tarkesh Esfahani +2 more
doaj +1 more source
Influenza and Other Respiratory Viruses, Volume 19, Issue 10, October 2025.ABSTRACT Background Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against coronaviruses, clarify molecular effects via bioassays and docking, and explore structure–activity relationships.
Marcela Safratova +11 more
wiley +1 more source
Studies on Cycloadducts of Thebaine and Thioaldehydes [PDF]
, 1993 A new route to the synthesis of 14beta-alkylmorphinans, of interest as potential analgesics, has been developed. Several such morphinans have been produced by desulphurisation of the Diels-Alder cycloadducts of thebaine and thioaldehydes, or of related ...
McQuillan, James Thomas
core
Journal of Medicinal Plants, 2019 Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami +5 more
doaj
Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)
Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni +5 more
wiley +1 more source