Results 61 to 70 of about 1,660 (216)

Effective Induction of Hairy Roots in Persian Poppy (Papaver bracteatum Lindl.) Using Sonication Method

Journal of Medicinal Plants, 2018
Background: Papaver bracteatum Lindl. Commonly known as Iranian poppy is an important medicinal plant due to the presence of benzylisoquinoline alkaloids. Objective: To evaluate the hairy root culture as a novel method for thebaine production.
N Qavami, M Azizi, F Yazdian, A Qaderi, H Nemati   +4 more
doaj  

Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway [PDF]

, 2018
Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum (opium poppy), which belongs to the non-heme 2-oxoglutarate/Fe(II)-dependent dioxygenases (ODD) family, is a key enzyme in the morphine biosynthesis pathway.
Anna Kluza, Tomasz Borowski, Quesne, Matthew, Kluza, Anna, Borowski, Tomasz, Wojdyla, Zuzanna, Kurpiewska, Katarzyna, Katarzyna Kurpiewska, Zuzanna Wojdyla, Niedzialkowska, Ewa, Kot, Ewa, Porebski, Przemyslaw J., Porębski, Przemysław J., Wojdyła, Zuzanna, Ewa Kot, Niedziałkowska, Ewa, Ewa Niedzialkowska, Przemyslaw J. Porebski, Matthew Quesne   +18 more
core   +1 more source

Analytical Review on Persian Poppy (Papaver bracteatum Lindl.) as a Native and Economical Medicinal Plant

Journal of Medicinal Plants, 2013
Persian poppy or great scarlet poppy (Papaver bracteatum Lindl.) is proposed as a new source of raw material for codeine production and addiction treatment. This species as a native plant is growing in North and West of Iran.
A Foroozandeh-Shahraki, A Mehrafarin, S Akhondzadeh, H Naghdi Badi, A Qaderi, R Hajiaghaee, F Khalighi-Sigaroodi, M Ghorbani Nahooji   +7 more
doaj  

Estimating General and Special Combining Abilities for Economic Traits in Turkish Hybrid Opium Poppy (Papaver somniferum L.) Lines. [PDF]

Journal of Medicinal Plants and By-products, 2017
Opiumpoppy (Papaver somniferum L.) is one of the important and oldest cultivated medicinal plant used to extract morphine, papaverine, thebaine, codeine and other alkaloids.
Negar Valizadeh, Neset Arslan, Amir Rahimi   +2 more
doaj  

A novel plasmid‐based experimental system in Saccharomyces cerevisiae that enables the introduction of 10 different plasmids into cells

FEBS Open Bio, Volume 14, Issue 12, Page 1955-1971, December 2024.
We developed the Saccharomyces cerevisiae strains termed Δ10 that exhibit auxotrophic behavior for 10 different nutrients and the plasmids with auxotrophic markers for use in Δ10 strains. Δ10 strains were able to maintain 10 types of plasmids by auxotrophic selection.
Geyao Dong, Tsuyoshi Nakai, Tetsuo Matsuzaki   +2 more
wiley   +1 more source

Structural analysis of a ligand‐triggered intermolecular disulfide switch in a major latex protein from opium poppy

Acta Crystallographica Section D, Volume 80, Issue 9, Page 675-685, September 2024.
Crystal structures of two cysteine‐to‐serine mutants of PR10‐10 help to reveal how a ligand‐induced conformational change is coupled to the formation of intermolecular disulfide bonds in plant pathogenesis‐related family 10 proteins involved in the biosynthesis of benzylisoquinoline alkaloids.Several proteins from plant pathogenesis‐related family 10 ...
Samuel C. Carr, Peter J. Facchini, Kenneth K. S. Ng   +2 more
wiley   +1 more source

Prediction of poppy thebaine alkaloid concentration using UAS remote sensing

, 2020
Alkaloid concentration, which represents the quality of industrial poppy, needs to be estimated in a spatially explicit manner to predict the value of crop prior to harvesting.
Iqbal, F (15738374), Arko Lucieer (14742862), Kara Barry (14731216)   +2 more
core  

Approaches to isolating a cDNA encoding thebaine synthase or morphine biosynthesis from opium poppy Papaver somniferum L. [PDF]

, 2006
Die Alkaloide des Benzylisochinolintyps kommen in ungefähr 2500 Strukturen vor. Zu ihnen gehören viele physiologisch aktive Substanzen. Innerhalb dieser Gruppe von Alkaloiden ist Morphin der pharmazeutisch wichtigste Vertreter. Es wird immer noch aus dem
Sabarna, Khaled
core   +1 more source

Strangers in a foreign land: ‘Yeastizing’ plant enzymes

Microbial Biotechnology, Volume 17, Issue 9, September 2024.
Many plant secondary metabolic enzymes need to be re‐engineered for optimal performance in yeast platforms due to poor adaptation to the foreign cellular environment. We highlight the challenges in ‘yeastizing’ plant enzymes and propose a data‐driven framework for learning the yeastizing rules from natural protein sequence variations.
Kristen Van Gelder, Steffen N. Lindner, Andrew D. Hanson, Juannan Zhou   +3 more
wiley   +1 more source

An industrially applicable Escherichia coli platform for bioconversion of thebaine to oripavine and codeine to morphine

, 2023
A whole cell Escherichia coli biotransformation platform converting thebaine to oripavine and codeine to morphine was demonstrated with industrially applicable yields (∼1.2 × 10-2 g L-1 h-1 or ∼1.2 × 10-1 g L-1 h-1), improving >13 400-fold upon morphine ...
Jarrold, A, Gras, SL, Li, X, Spencer, GWK   +3 more
core   +1 more source