Results 51 to 60 of about 1,809 (150)
Summary Pathogenesis‐related (PR) proteins are diverse stress‐ or pathogen‐induced proteins. Some are associated with specialised metabolism, including proposed functions for anthocyanin biosynthesis. However, data are limited to a few angiosperm species, and the mode(s) of action are uncertain.
Yanfei Zhou +8 more
wiley +1 more source
Background: Papaver bracteatum Lindl. Commonly known as Iranian poppy is an important medicinal plant due to the presence of benzylisoquinoline alkaloids. Objective: To evaluate the hairy root culture as a novel method for thebaine production.
N Qavami +4 more
doaj
Evaluation of ultrasound effects on growth and biochemical characteristics of Iranian poppy cell cultures and thebaine production [PDF]
Low-energy ultrasound shows multiple physiological effects on plant cells and tissues, and has numerous applications in plant biotechnology, especially in elicitation of secondary metabolites production.
Ali Asghar Askari +4 more
doaj
Characterization of Opioid Agonist Morphine Derivatives with Emphasis on Medicinal Chemistry
The aim of synthesizing new opioid compounds is to produce drugs that are more potent, less addictive, and have fewer side effects, such as respiratory depression and constipation. To achieve this, we evaluated the basicity, lipophilicity, and permeability of 30 opioid compounds, including 11 newly synthesized ones, to better understand the ...
Alaa Malik +7 more
wiley +1 more source
Persian poppy or great scarlet poppy (Papaver bracteatum Lindl.) is proposed as a new source of raw material for codeine production and addiction treatment. This species as a native plant is growing in North and West of Iran.
A Foroozandeh-Shahraki +7 more
doaj
Estimating General and Special Combining Abilities for Economic Traits in Turkish Hybrid Opium Poppy (Papaver somniferum L.) Lines. [PDF]
Opiumpoppy (Papaver somniferum L.) is one of the important and oldest cultivated medicinal plant used to extract morphine, papaverine, thebaine, codeine and other alkaloids.
Negar Valizadeh +2 more
doaj
We developed the Saccharomyces cerevisiae strains termed Δ10 that exhibit auxotrophic behavior for 10 different nutrients and the plasmids with auxotrophic markers for use in Δ10 strains. Δ10 strains were able to maintain 10 types of plasmids by auxotrophic selection.
Geyao Dong +2 more
wiley +1 more source
Crystal structures of two cysteine‐to‐serine mutants of PR10‐10 help to reveal how a ligand‐induced conformational change is coupled to the formation of intermolecular disulfide bonds in plant pathogenesis‐related family 10 proteins involved in the biosynthesis of benzylisoquinoline alkaloids.Several proteins from plant pathogenesis‐related family 10 ...
Samuel C. Carr +2 more
wiley +1 more source
Strangers in a foreign land: ‘Yeastizing’ plant enzymes
Many plant secondary metabolic enzymes need to be re‐engineered for optimal performance in yeast platforms due to poor adaptation to the foreign cellular environment. We highlight the challenges in ‘yeastizing’ plant enzymes and propose a data‐driven framework for learning the yeastizing rules from natural protein sequence variations.
Kristen Van Gelder +3 more
wiley +1 more source
N-Demethylation and N-oxidation of thebaine, an isoquinoline alkaloid by Mucor piriformis
Northebaine was identified as the major metabolite formed during the biotransformation of thebaine by Mucor piriformis. Minor metabolites identified are isomeric thebaine N-oxides.
Sridhar, GR +3 more
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