Results 31 to 40 of about 3,283 (227)

Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]

open access: yes, 2018
The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J.   +6 more
core   +5 more sources

Study of karyological characteristics in several accessions of Papaver bracteatum Lindl. [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2012
Iranian poppy (Papaver bracteatum Lindl.) is one of the most important medicinal plants which its main alkaloid is thebaine. In this study karyological characteristics of five accessions of Papaver bracteatum Lindl were investigated using Aceto-Iron ...
Reza Farjami Nezhad   +3 more
doaj   +1 more source

Evaluation of the Transfer and Occurrence of Opium Alkaloids in Poppy Seed Teas Using Preconcentrations with µSPEed® Followed by GC-MS Analysis

open access: yesChemosensors, 2023
Intoxication due to the consumption of poppy seed teas has been reported due to their contamination with opium alkaloids (OAs). In this work, an efficient methodology based on microsolid-phase extraction (µSPEed®) followed by gas chromatography–mass ...
Gema Casado-Hidalgo   +4 more
doaj   +1 more source

The Power of Yeast

open access: yesYeast, Volume 42, Issue 12, Page 303-310, December 2025.
ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley   +1 more source

Pharmaceuticals that contain polycyclic hydrocarbon scaffolds [PDF]

open access: yes, 2015
Numerous variations on structural motifs exist within pharmaceutical compounds that have entered the clinic. These variations have amounted over many decades based on years of drug development associated with screening natural products and de novo ...
Stockdale, Tegan P., Williams, Craig M.
core   +1 more source

Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis

open access: yesChemCatChem, Volume 17, Issue 21, November 10, 2025.
Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen   +4 more
wiley   +1 more source

A Systematic Review on Main Chemical Constituents of Papaver bracteatum

open access: yesJournal of Medicinal Plants, 2015
Papaver bracteatum Lindly (Papaveraceae) is an endemic species of Iran which has economic importance in drug industries. The main alkaloid of the plant is thebaine which is used as a precursor of the semi-synthetic and synthetic compounds including ...
M Soleymankhani   +5 more
doaj  

Endophytic Consortium With Diverse Gene-Regulating Capabilities of Benzylisoquinoline Alkaloids Biosynthetic Pathway Can Enhance Endogenous Morphine Biosynthesis in Papaver somniferum

open access: yesFrontiers in Microbiology, 2019
Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray   +5 more
doaj   +1 more source

Variation of seed characteristic from natural and artificial selection in the genus Papaver [PDF]

open access: yes, 2015
Papaveraceae is a mediterranean plant family with an important scientific, commercial and ethnobotanical interest. Includes wild species, which are distributed throughout the Spanish territory, as Papaver rhoeas, P. dubium, P. bracteatum, P. hybridum and
Martín-Clemente, Elena   +1 more
core  

Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure–Activity Relationship

open access: yesInfluenza and Other Respiratory Viruses, Volume 19, Issue 10, October 2025.
ABSTRACT Background Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against coronaviruses, clarify molecular effects via bioassays and docking, and explore structure–activity relationships.
Marcela Safratova   +11 more
wiley   +1 more source

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