Results 31 to 40 of about 1,809 (150)

Thebaine Synthase: A New Enzyme in the Morphine Pathway in

open access: yesNatural Product Communications, 2007
Along the poppy morphine biosynthetic pathway, the transition from salutaridinol-7-O-acetate to thebaine had previously been claimed to proceed non-enzymatically between pH 8–9. At pH 6–7, the acetate was transformed to an azonine derivative.
Ursula Fisinger   +2 more
doaj   +1 more source

Evaluation of the Transfer and Occurrence of Opium Alkaloids in Poppy Seed Teas Using Preconcentrations with µSPEed® Followed by GC-MS Analysis

open access: yesChemosensors, 2023
Intoxication due to the consumption of poppy seed teas has been reported due to their contamination with opium alkaloids (OAs). In this work, an efficient methodology based on microsolid-phase extraction (µSPEed®) followed by gas chromatography–mass ...
Gema Casado-Hidalgo   +4 more
doaj   +1 more source

Study of karyological characteristics in several accessions of Papaver bracteatum Lindl. [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2012
Iranian poppy (Papaver bracteatum Lindl.) is one of the most important medicinal plants which its main alkaloid is thebaine. In this study karyological characteristics of five accessions of Papaver bracteatum Lindl were investigated using Aceto-Iron ...
Reza Farjami Nezhad   +3 more
doaj   +1 more source

Oxycodone: A Pain‐Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia–Reperfusion Injury

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
In the realm of cardiovascular diseases, myocardial ischemia–reperfusion injury (MIRI) is known as one of the main life‐threatening conditions with significant morbidity and mortality. Although some therapeutic approaches, like pharmacological treatments and ischemic preconditioning, have been suggested for MIRI, offering a functional approach with ...
Mehdi Dehghani Firoozabadi   +3 more
wiley   +1 more source

Endophytic Consortium With Diverse Gene-Regulating Capabilities of Benzylisoquinoline Alkaloids Biosynthetic Pathway Can Enhance Endogenous Morphine Biosynthesis in Papaver somniferum

open access: yesFrontiers in Microbiology, 2019
Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray   +5 more
doaj   +1 more source

A Systematic Review on Main Chemical Constituents of Papaver bracteatum

open access: yesJournal of Medicinal Plants, 2015
Papaver bracteatum Lindly (Papaveraceae) is an endemic species of Iran which has economic importance in drug industries. The main alkaloid of the plant is thebaine which is used as a precursor of the semi-synthetic and synthetic compounds including ...
M Soleymankhani   +5 more
doaj  

Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli

open access: yesNature Communications, 2016
Opiates—the gold standard for pain relief—are currently produced by extraction from opium poppies. Here the authors show that bacteria can serve as an efficient and flexible platform for the production of opiates by demonstrating the total synthesis of ...
Akira Nakagawa   +9 more
doaj   +1 more source

The Power of Yeast

open access: yesYeast, Volume 42, Issue 12, Page 303-310, December 2025.
ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley   +1 more source

The Effect of L-tyrosine on Thebaine Production in Cell Suspension Culture of Iranian Poppy (Papaver bracteatum)

open access: yesJournal of Medicinal Plants, 2016
Background: Using of elicitors and different compounds in cell suspension culture is an effective strategy for enhancement and improvement of important secondary metabolites production in in vitro conditions.
R Farjaminezhad   +3 more
doaj  

In Vitro Polyploidy Induction in Persian Poppy (Papaver bracteatum Lindl.)

open access: yesCaryologia, 2020
Papaver bracteatum Lindl. grows as a wild perennial medicinal plant in Northern Iran and is known mainly for its high amounts of the pharmaceutically valuable alkaloid of thebaine. In vitro production of tetraploid P.
Saeed Tarkesh Esfahani   +2 more
doaj   +1 more source

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