Results 31 to 40 of about 1,919 (204)
Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova +2 more
wiley +1 more source
Biomimetic synthesis of neodihydrothebaine and bractazonine from thebaine
Photochemical irradiation of the morphinan alkaloid thebaine 1 followed by reduction, affords the dibenz[d,f]azonine alkaloids neodihydrothebaine 2 and bractazonine 3, in a sequence paralleling the proposed biosynthesis of these alkaloids in Papaver ...
Theuns, H.G. +3 more
core +2 more sources
The Physiological Action of Thebain [PDF]
n ...
openaire +1 more source
The synthesis of potential analgesics derived from thebaine [PDF]
The thesis describes the synthesis of novel bridged thebaine derivatives with heterocyclic rings attached to C-7 and a study of the associated chemistry. Use has been made of the α-hydrazide (3) formed from the α-ester (2), itself prepared by Diels-Alder
Michael Burton (4178776)
core +3 more sources
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke +3 more
wiley +1 more source
Direct and Simple O-Demethylation of Thebaine to Oripavine
Direct and Simple O-Demethylation of Thebaine to ...
Andrew Coop (1416964) +2 more
core +1 more source
Thebaine Synthase: A New Enzyme in the Morphine Pathway in
Along the poppy morphine biosynthetic pathway, the transition from salutaridinol-7-O-acetate to thebaine had previously been claimed to proceed non-enzymatically between pH 8–9. At pH 6–7, the acetate was transformed to an azonine derivative.
Ursula Fisinger +2 more
doaj +1 more source
Intoxication due to the consumption of poppy seed teas has been reported due to their contamination with opium alkaloids (OAs). In this work, an efficient methodology based on microsolid-phase extraction (µSPEed®) followed by gas chromatography–mass ...
Gema Casado-Hidalgo +4 more
doaj +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Study of karyological characteristics in several accessions of Papaver bracteatum Lindl. [PDF]
Iranian poppy (Papaver bracteatum Lindl.) is one of the most important medicinal plants which its main alkaloid is thebaine. In this study karyological characteristics of five accessions of Papaver bracteatum Lindl were investigated using Aceto-Iron ...
Reza Farjami Nezhad +3 more
doaj +1 more source

