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Thebaine is naturally occurring alkaloid which is of great importance in the pharmaceutical industry and up to now there is not a Pharmacopoeial monograph for this compound.
Marija Spasevska +2 more
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Behavioral effects of thebaine in the rhesus monkey [PDF]
Three experiments were conducted with rhesus monkeys to assess some behavioral effects of the opium alkaloid, thebaine, in relation to its dependence liability. The concurrent intramuscular administration of naloxone did not antagonize the rate-decreasing effects of thebaine on a fixed-ratio (FR) schedule of food-reinforced responding.
Woods, James H. +2 more
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In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present in Papaver somniferum L. poppy seeds. In this study, a simple, rapid and efficient method has been optimised to determine
Gema Casado-Hidalgo +3 more
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Separation and identification of a number of alkaloids and some phenols from two species of plants of the genus Euphorbia grown in Nineveh Governorate. [PDF]
In this research, a number of chemical compounds were estimated and identified in the crude extract of both E. helioscopia and E. peplus species, as it was noted that there were about twenty alkaloid compounds in them, and It was, also, noted that there ...
Enas Qasim, Jehan Al-Hatem, Lubna abbas
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The in vitro shoot culture of a T-DNA insertional mutant of Papaver somniferum L. established by the infection of Agrobacterium rhizogenes MAFF03-01724 accumulated thebaine instead of morphine as a major opium alkaloid.
Kayo Yoshimatsu +3 more
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Update of the Scientific Opinion on opium alkaloids in poppy seeds
Poppy seeds are obtained from the opium poppy (Papaver somniferum L.). They are used as food and to produce edible oil. The opium poppy plant contains narcotic alkaloids such as morphine and codeine.
EFSA Panel on Contaminants in the Food Chain (CONTAM) +32 more
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The aim of this study is to determine the alkaloid and oil rates contents of some poppy (Papaver somniferum L.) varieties, such as morphine, codeine, oripavine, thebaine, noscapine and papaverine, which are planted as winter and summer. Five varieties of
Levent Yazıcı, Güngör Yılmaz
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The Physiological Action of Thebain [PDF]
n ...
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Thebaine Synthase: A New Enzyme in the Morphine Pathway in
Along the poppy morphine biosynthetic pathway, the transition from salutaridinol-7-O-acetate to thebaine had previously been claimed to proceed non-enzymatically between pH 8–9. At pH 6–7, the acetate was transformed to an azonine derivative.
Ursula Fisinger +2 more
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Intoxication due to the consumption of poppy seed teas has been reported due to their contamination with opium alkaloids (OAs). In this work, an efficient methodology based on microsolid-phase extraction (µSPEed®) followed by gas chromatography–mass ...
Gema Casado-Hidalgo +4 more
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