Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Heroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M +4 more
europepmc +2 more sources
Update on Opium Alkaloids in Food: Exploring Their Occurrence, Effect of Culinary Processing and Advances in Analytical Methodologies. [PDF]
ABSTRACT Following the implementation of the new European legislation on opium alkaloids (OAs) in food in 2023, scientific research has focused on developing analytical methodologies to determine the presence of these compounds in different foods. However, health authorities continue to suggest further studies to evaluate the occurrence of main OAs and
Casado-Hidalgo G +2 more
europepmc +2 more sources
Traces of Use: Uncovering Drug Use Insights From Paraphernalia Analysis. [PDF]
ABSTRACT Introduction The residue analysis of disposed paraphernalia from people who inject drugs is a novel way to discern drug taking behaviours. This study aimed to investigate the presence of conventional and novel psychoactive substances (NPS) in drug paraphernalia in South Australia.
Keller EL +5 more
europepmc +2 more sources
Modification of Gene Expression Involved in Alkaloid Production in Opium Poppy by VIGS Combined With Pretreatment of Macerozyme Enzyme. [PDF]
ABSTRACT Papaver somniferum L., a medicinal plant renowned for its pharmaceutical alkaloids, has captivated scientific interest due to its rich secondary metabolite profile. This study explores a novel approach to manipulating alkaloid biosynthesis pathways by integrating virus‐induced gene silencing (VIGS) with macerozyme enzyme pretreatment ...
Özcan DE +4 more
europepmc +2 more sources
Oxycodone: A Pain-Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia-Reperfusion Injury. [PDF]
In the realm of cardiovascular diseases, myocardial ischemia–reperfusion injury (MIRI) is known as one of the main life‐threatening conditions with significant morbidity and mortality. Although some therapeutic approaches, like pharmacological treatments and ischemic preconditioning, have been suggested for MIRI, offering a functional approach with ...
Firoozabadi MD +2 more
europepmc +2 more sources
I am old enough to have taken part in the international project to sequence the first eukaryotic genome—that of Saccharomyces cerevisiae—which was released in 1996. Twenty years later, scientists from academic and commercial institutions are now involved
RINALDI, Teresa
core +1 more source
Background: Papaver bracteatum Lindl. (Persian poppy) has a very long history as the major source of natural alkaloids. Among Papaver species, Persian poppy can be considered as a rich source of thebaine.
Alireza Habibzade +2 more
doaj
Thebaine is naturally occurring alkaloid which is of great importance in the pharmaceutical industry and up to now there is not a Pharmacopoeial monograph for this compound.
Marija Spasevska +2 more
doaj +1 more source
In recent years, health authorities have become increasingly concerned about preventing consumer exposure to opium alkaloids present in Papaver somniferum L. poppy seeds. In this study, a simple, rapid and efficient method has been optimised to determine
Gema Casado-Hidalgo +3 more
doaj +1 more source
Separation and identification of a number of alkaloids and some phenols from two species of plants of the genus Euphorbia grown in Nineveh Governorate. [PDF]
In this research, a number of chemical compounds were estimated and identified in the crude extract of both E. helioscopia and E. peplus species, as it was noted that there were about twenty alkaloid compounds in them, and It was, also, noted that there ...
Enas Qasim, Jehan Al-Hatem, Lubna abbas
doaj +1 more source

