Evaluation of the Immunity Activity of Glycyrrhizin in AR Mice
Molecules, 2012 In this study, we evaluated effect of glycyrrhizin on immunity function in allergic rhinitis (AR) mice. The AR mice model were induced by dripping ovalbumin in physiological saline (2 mg mL−1, 10 μL) into the bilateral nasal cavities using a micropipette.
Ai-Guo Zhou, Xiao-Lan Li
exaly +4 more sources
Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]
PLoS ONE, 2011 Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Martin Michaelis +6 more
doaj +2 more sources
Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma [PDF]
Frontiers in Pharmacology, 2023 Asthma is a common chronic respiratory disease, which causes inflammation and airway stenosis, leading to dyspnea, wheezing and chest tightness. Using transgelin-2 as a target, we virtually screened the lead compound glycyrrhizin from the self-built ...
Jian-Hong Qi +7 more
doaj +2 more sources
The potential of glycyrrhizin and licorice extract in combating COVID-19 and associated conditions
Phytomedicine Plus, 2021 Background: Several recent studies have stated that glycyrrhizin and licorice extract are present in most traditional Chinese medicine formulas used against SARS-CoV-2 in China.
Adel A Gomaa
exaly +3 more sources
Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro
BMC Molecular and Cell Biology, 2023 Inflammation plays a crucial role in the progression of Subacute Ruminal Acidosis (SARA). The experiment was designed to investigate anti-inflammatory effects of glycyrrhizin on goats ruminal epithelial cells (GREC) which were induced SARA by ...
Junfeng Liu +6 more
doaj +2 more sources
Glycyrrhizin's Potential to Modulate Feeding Behaviour by Neutralizing Reduced Feed Intake in Inflamed Arian Broilers [PDF]
Veterinary Medicine and ScienceBackground The Arian broiler, an important native Iranian breed, shows heightened sensitivity to metabolic disturbances caused by lipopolysaccharide (LPS). This study evaluated whether glycyrrhizin could mitigate LPS‐associated physiological disruptions.
Mitra Nowrouzpour +2 more
doaj +2 more sources
Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis [PDF]
Renal FailureContrast-induced acute kidney injury (CI-AKI) is the third leading cause of AKI, but there are no effective preventive or therapeutic measures in clinical practice. Glycyrrhizin, a bioactive compound isolated from the Glycyrrhiza glabra L., exhibits anti-
Fang-yuan Tian +9 more
doaj +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background High‐mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome and systemic immune response after cardiac arrest (CA) in rabbits.
Emilie Boissady +10 more
doaj +1 more source
Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells [PDF]
PeerJ, 2020 Background Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory ...
Yanni Gui +5 more
doaj +2 more sources
Pharmacology Research & Perspectives, 2021 Coronary microembolization (CME)‐induced inflammation and cardiomyocyte apoptosis are two key factors contributing to CME‐induced myocardial dysfunction.
Yonggang Yuan +3 more
doaj +1 more source