Results 1 to 10 of about 6,873 (163)

Glycyrrhizin's Potential to Modulate Feeding Behaviour by Neutralizing Reduced Feed Intake in Inflamed Arian Broilers [PDF]

Veterinary Medicine and Science
Background The Arian broiler, an important native Iranian breed, shows heightened sensitivity to metabolic disturbances caused by lipopolysaccharide (LPS). This study evaluated whether glycyrrhizin could mitigate LPS‐associated physiological disruptions.
Mitra Nowrouzpour, Amin Rahdari, Farshid Hamidi   +2 more
doaj   +2 more sources

Glycyrrhizin Effectively Inhibits SARS-CoV-2 Replication by Inhibiting the Viral Main Protease

Viruses, 2021
The outbreak of SARS-CoV-2 developed into a global pandemic affecting millions of people worldwide. Despite one year of intensive research, the current treatment options for SARS-CoV-2 infected people are still limited. Clearly, novel antiviral compounds
Carina Elsner, Ulf Dittmer, Adalbert Krawczyk   +2 more
exaly   +3 more sources

Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis [PDF]

Renal Failure
Contrast-induced acute kidney injury (CI-AKI) is the third leading cause of AKI, but there are no effective preventive or therapeutic measures in clinical practice. Glycyrrhizin, a bioactive compound isolated from the Glycyrrhiza glabra L., exhibits anti-
Fang-yuan Tian, Kun Liu, Zhi-yao Tang, Ge Zhou, Guang-liang Zhou, Rui-feng Chen, Hao-bo Liu, Wei-jin Fang, Xiao-cong Zuo, Ling-yun Zhou   +9 more
doaj   +2 more sources

Evaluation of the Immunity Activity of Glycyrrhizin in AR Mice

Molecules, 2012
In this study, we evaluated effect of glycyrrhizin on immunity function in allergic rhinitis (AR) mice. The AR mice model were induced by dripping ovalbumin in physiological saline (2 mg mL−1, 10 μL) into the bilateral nasal cavities using a micropipette.
Ai-Guo Zhou, Xiao-Lan Li
exaly   +3 more sources

The potential of glycyrrhizin and licorice extract in combating COVID-19 and associated conditions

Phytomedicine Plus, 2021
Background: Several recent studies have stated that glycyrrhizin and licorice extract are present in most traditional Chinese medicine formulas used against SARS-CoV-2 in China.
Adel A. Gomaa, Yasmin A. Abdel-Wadood
doaj   +1 more source

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]

PLoS ONE, 2011
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Martin Michaelis, Janina Geiler, Patrizia Naczk, Patchima Sithisarn, Anke Leutz, Hans Wilhelm Doerr, Jindrich Cinatl   +6 more
doaj   +1 more source

High‐Mobility Group Box 1–Signaling Inhibition With Glycyrrhizin Prevents Cerebral T‐Cell Infiltration After Cardiac Arrest

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background High‐mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome and systemic immune response after cardiac arrest (CA) in rabbits.
Emilie Boissady, Yara Abi Zeid Daou, Estelle Faucher, Matthias Kohlhauer, Fanny Lidouren, Cynthia El Hedjaj, Sophie Chateau‐Joubert, Hakim Hocini, Sophie Hue, Bijan Ghaleh, Renaud Tissier   +10 more
doaj   +1 more source

Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro

BMC Molecular and Cell Biology, 2023
Inflammation plays a crucial role in the progression of Subacute Ruminal Acidosis (SARA). The experiment was designed to investigate anti-inflammatory effects of glycyrrhizin on goats ruminal epithelial cells (GREC) which were induced SARA by ...
Junfeng Liu, Bei Ma, Guang Hao, DuoDuo Su, Tianyang Wang, Ze Ding, Xuefeng Guo   +6 more
doaj   +1 more source

Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma

Frontiers in Pharmacology, 2023
Asthma is a common chronic respiratory disease, which causes inflammation and airway stenosis, leading to dyspnea, wheezing and chest tightness. Using transgelin-2 as a target, we virtually screened the lead compound glycyrrhizin from the self-built ...
Jian-Hong Qi, Dong-Chuan Xu, Xiao-Long Wang, Xiao-Long Wang, Xiao-Long Wang, Ding-Yuan Cai, Yi Wang, Wei Zhou   +7 more
doaj   +1 more source

Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells [PDF]

PeerJ, 2020
Background Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory ...
Yanni Gui, Jian Sun, Wenjie You, Yuanhui Wei, Han Tian, Shujuan Jiang   +5 more
doaj   +2 more sources