Results 21 to 30 of about 6,892 (182)

Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: The effects of glycyrrhizin treatment in lung cancer remain undetermined, despite extensive studies of the anti-tumor activities of glycyrrhizin. Methods: Lung adenocarcinoma A549 and NCI-H23 cell lines were used in this study.
Run-Yue Huang   +5 more
doaj   +1 more source

Effects of glycyrrhizin on the pharmacokinetics of paeoniflorin in rats and its potential mechanism

open access: yesPharmaceutical Biology, 2019
Context: Paeoniflorin is reported to possess numerous pharmacological activities. Paeoniflorin and glycyrrhizin are always used together for the treatment of disease in China clinics; however, the drug–drug interaction between glycyrrhizin and ...
Hongjuan Sun, Jingfeng Wang, Juan Lv
doaj   +1 more source

Micelle Formation of Monoammonium Glycyrrhizinate

open access: yesJournal of Oleo Science, 2021
Monoammonium glycyrrhizinate is produced by the neutralization of glycyrrhizic acid from plant licorice with ammonia. In this study, the physicochemical properties of aqueous monoammonium glycyrrhizinate were investigated from the viewpoint of surface chemistry.
Matsuoka, Keisuke   +4 more
openaire   +3 more sources

Beneficial Effects of Glycyrrhizin in Chronic Periodontitis Through the Inhibition of Inflammatory Response

open access: yesDose-Response, 2020
Elevated inflammatory cytokines and high mobility group box 1 (HMGB1) production are associated with chronic periodontitis (CP). Glycyrrhizin is the major constituent of Glycyrrhiza glabra. L. (Fabaceae) root with anti-inflammation activities. This study
Yaru Sun   +3 more
doaj   +1 more source

Computational and In Vitro Experimental Investigations Reveal Anti-Viral Activity of Licorice and Glycyrrhizin against Severe Acute Respiratory Syndrome Coronavirus 2

open access: yesPharmaceuticals, 2021
Without effective antivirals, the COVID-19 pandemic will likely continue to substantially affect public health. Medicinal plants and phytochemicals are attractive therapeutic options, particularly those targeting viral proteins essential for replication ...
Ahmed M. Tolah   +5 more
doaj   +1 more source

Research progress of glycyrrhizin in the treatment of osteoarthritis

open access: yesKouqiang hemian waike zazhi
Glycyrrhizin is extracted from licorice root and has anti-inflammatory, antioxidant, anti-tumor, anti-viral and other effects. At present, there are few studies on the role and mechanism of glycyrrhizin in osteoarthritis.
HU Zhihui, LONG Xing
doaj   +1 more source

Application of Monoclonal Antibodies against Bioactive Natural Products: Eastern Blotting and Preparation of Knockout Extract

open access: yesInternational Journal of Analytical Chemistry, 2012
Matrix-assisted laser desorption/ionization (MALDI) tof mass spectrometry was used for the confirmation of hapten number in synthesized antigen. As application of MAb, the MAbs against ginsenosides and glycyrrhizin have been prepared resulting in the ...
Hiroyuki Tanaka   +8 more
doaj   +1 more source

Physiological correlation between glycyrrhizin, glycyrrhizin‐binding lipoxygenase and casein kinase II [PDF]

open access: yesFEBS Letters, 1996
By means of glycyrrhizin (GL)‐affinity column chromatography, a GL‐binding lipoxygenase (gbLOX) was selectively purified from the partially purified soybean LOX‐1 fraction. Polypeptide analysis of the purified gbLOX by SDS‐PAGE detected two distinct polypeptides (p96 and p94), which were identical to LOX‐3 as determined by their partial N‐terminal ...
Shimoyama, Yoshihito   +5 more
openaire   +2 more sources

Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model

open access: yesJournal of Immunology Research, 2014
Upregulated TLRs are observed in the serum of animals following experimental subarachnoid hemorrhage. This study was to examine glycyrrhizin’s effect on proinflammatory cytokines and TLRs in SAH rats.
Chih-Zen Chang   +2 more
doaj   +1 more source

Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2023
Pexidartinib offered a new therapeutic option for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) who were refractory to surgical treatment and had severe morbidity or functional limitations. Meanwhile, the metabolism of pexidartinib
Yanding Su   +5 more
doaj   +1 more source

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