Results 21 to 30 of about 10,603 (261)

Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects [PDF]

Frontiers in Pharmacology
BackgroundFor patients with epilepsy, antiseizure medication remains the primary treatment; however, it is ineffective in approximately 30% of cases. These patients experience progressive neuronal damage and poor outcomes.
Lei Wei, Sijie Ou, Youshi Meng, Lanfeng Sun, Lin Zhang, Yuling Lu, Yuan Wu   +6 more
doaj   +2 more sources

Therapeutic potential of glycyrrhizin in nervous system diseases. [PDF]

Chin Med J (Engl)
An J, Han M, Chen P, Wang L, Gao L, Zhou Z, Huang S, Du J, Peng F.   +8 more
europepmc   +2 more sources

Dietary glycyrrhizin enhances reproductive performance by improving intestinal microbiota, liver lipid metabolism and ovarian senescence in aged breeder hens. [PDF]

J Anim Sci Biotechnol
Huang Z, Liu H, Wang G, Ge H, Shi Y, Feng J, Li C, Zhang M.   +7 more
europepmc   +3 more sources

Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis

BMC Immunology, 2021
Background The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood.
Huang Qiong, Ling Han, Nanxue Zhang, Huyan Chen, Kexiang Yan, Zhenghua Zhang, Ying Ma, Jinhua Xu   +7 more
doaj   +1 more source

Effect of glycyrrhizin on pseudomonal skin infections in human-mouse chimeras. [PDF]

PLoS ONE, 2014
In our previous studies, peripheral blood lineage(-)CD34(+)CD31(+) cells (CD31(+) IMC) appearing in severely burned patients have been characterized as inhibitor cells for the production of β-defensins (HBDs) by human epidermal keratinocytes (NHEK).
Shohei Yoshida, Jong O Lee, Kiwamu Nakamura, Sumihiro Suzuki, David N Hendon, Makiko Kobayashi, Fujio Suzuki   +6 more
doaj   +1 more source

Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits Helicobacter pylori infection

Molecular Medicine, 2023
Background Helicobacter pylori is a key agent for causing gastric complications linked with gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular homeostasis. However, H. pylori have evolved the ability to usurp
Uzma Khan, Bipul Chandra Karmakar, Priyanka Basak, Sangita Paul, Animesh Gope, Deotima Sarkar, Asish Kumar Mukhopadhyay, Shanta Dutta, Sushmita Bhattacharya   +8 more
doaj   +1 more source

Glycyrrhizin Effectively Inhibits SARS-CoV-2 Replication by Inhibiting the Viral Main Protease

Viruses, 2021
The outbreak of SARS-CoV-2 developed into a global pandemic affecting millions of people worldwide. Despite one year of intensive research, the current treatment options for SARS-CoV-2 infected people are still limited. Clearly, novel antiviral compounds
Lukas van de Sand, Maren Bormann, Mira Alt, Leonie Schipper, Christiane Silke Heilingloh, Eike Steinmann, Daniel Todt, Ulf Dittmer, Carina Elsner, Oliver Witzke, Adalbert Krawczyk   +10 more
doaj   +1 more source

Glycyrrhizin [PDF]

Archiv der Pharmazie
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  +4 more sources

Utilization of Glycyrrhizin and Licorice Extract as Natural Sweetener in Some Food Products and Biological Impacts [PDF]

Journal of Food and Dairy Sciences, 2017
Replacing sucrose with safe natural intense sweeteners has importance in health concerns as a way to produce healthy foods with low caloric value. The present study has been carried out to utilize glycyrrhizin and licorice extract (LE) from Glycyrrhiza ...
Mona Massoud, Amal Abd El-Razek, M. Abd El-Lahot, E. Gomaa   +3 more
doaj   +1 more source

Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM

Molecules, 2021
Phosphatidylglycerols represent a large share of the lipids in the plasmamembrane of procaryotes. Therefore, this study investigates the role of charged lipids in the plasma membrane with respect to the interaction of the antiviral saponin glycyrrhizin ...
Carina Dargel, Friederike Gräbitz-Bräuer, Ramsia Geisler, Pascal Fandrich, Yvonne Hannappel, Lionel Porcar, Thomas Hellweg   +6 more
doaj   +1 more source