Results 21 to 30 of about 8,780 (213)

Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis [PDF]

Renal Failure
Contrast-induced acute kidney injury (CI-AKI) is the third leading cause of AKI, but there are no effective preventive or therapeutic measures in clinical practice. Glycyrrhizin, a bioactive compound isolated from the Glycyrrhiza glabra L., exhibits anti-
Fang-yuan Tian, Kun Liu, Zhi-yao Tang, Ge Zhou, Guang-liang Zhou, Rui-feng Chen, Hao-bo Liu, Wei-jin Fang, Xiao-cong Zuo, Ling-yun Zhou   +9 more
doaj   +2 more sources

EST analysis reveals putative genes involved in glycyrrhizin biosynthesis [PDF]

BMC Genomics, 2010
Background Glycyrrhiza uralensis is one of the most popular medicinal plants in the world and is also widely used in the flavoring of food and tobacco.
Wang Ning, Yao Hui, Wu Qiong, Sun Yong-Zhen, Song Jing-Yuan, Sun Chao, Luo Hong-Mei, Li Ying, Steinmetz André, Chen Shi-Lin   +9 more
doaj   +2 more sources

Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats

Brazilian Journal of Medical and Biological Research, 2007
Massive hepatectomy associated with infection induces liver dysfunction, or even multiple organ failure and death. Glycyrrhizin has been shown to exhibit anti-oxidant and anti-inflammatory activities.
B. Tang, H. Qiao, F. Meng, X. Sun
doaj   +1 more source

High‐Mobility Group Box 1–Signaling Inhibition With Glycyrrhizin Prevents Cerebral T‐Cell Infiltration After Cardiac Arrest

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background High‐mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome and systemic immune response after cardiac arrest (CA) in rabbits.
Emilie Boissady, Yara Abi Zeid Daou, Estelle Faucher, Matthias Kohlhauer, Fanny Lidouren, Cynthia El Hedjaj, Sophie Chateau‐Joubert, Hakim Hocini, Sophie Hue, Bijan Ghaleh, Renaud Tissier   +10 more
doaj   +1 more source

Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells [PDF]

PeerJ, 2020
Background Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory ...
Yanni Gui, Jian Sun, Wenjie You, Yuanhui Wei, Han Tian, Shujuan Jiang   +5 more
doaj   +2 more sources

Protective effect of glycyrrhizin on coronary microembolization‐induced myocardial dysfunction in rats

Pharmacology Research & Perspectives, 2021
Coronary microembolization (CME)‐induced inflammation and cardiomyocyte apoptosis are two key factors contributing to CME‐induced myocardial dysfunction.
Yonggang Yuan, Bing Li, Wanzhong Peng, Zesheng Xu   +3 more
doaj   +1 more source

Extraction and purification of enriched glycyrrhizin extract [PDF]

, 2023
03.05.2025 tarihine kadar kullanımı yazar tarafından kısıtlanmıştır.Glisirizin, meyan kökü bitkisinin en önemli etken maddesidir. Bu tez çalışması glisirizin eldesi ve saflaştırılması için metot geliştirilmesi üzerinedir.
Karagül, Bora
core   +2 more sources

Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis

BMC Immunology, 2021
Background The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood.
Huang Qiong, Ling Han, Nanxue Zhang, Huyan Chen, Kexiang Yan, Zhenghua Zhang, Ying Ma, Jinhua Xu   +7 more
doaj   +1 more source

Effect of glycyrrhizin on pseudomonal skin infections in human-mouse chimeras. [PDF]

PLoS ONE, 2014
In our previous studies, peripheral blood lineage(-)CD34(+)CD31(+) cells (CD31(+) IMC) appearing in severely burned patients have been characterized as inhibitor cells for the production of β-defensins (HBDs) by human epidermal keratinocytes (NHEK).
Shohei Yoshida, Jong O Lee, Kiwamu Nakamura, Sumihiro Suzuki, David N Hendon, Makiko Kobayashi, Fujio Suzuki   +6 more
doaj   +1 more source

Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits Helicobacter pylori infection

Molecular Medicine, 2023
Background Helicobacter pylori is a key agent for causing gastric complications linked with gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular homeostasis. However, H. pylori have evolved the ability to usurp
Uzma Khan, Bipul Chandra Karmakar, Priyanka Basak, Sangita Paul, Animesh Gope, Deotima Sarkar, Asish Kumar Mukhopadhyay, Shanta Dutta, Sushmita Bhattacharya   +8 more
doaj   +1 more source