Results 41 to 50 of about 14,486 (271)

Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2023
Pexidartinib offered a new therapeutic option for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) who were refractory to surgical treatment and had severe morbidity or functional limitations. Meanwhile, the metabolism of pexidartinib
Yanding Su   +5 more
doaj   +1 more source

Glycyrrhizin Inhibits SARS-CoV-2 Entry into Cells by Targeting ACE2

open access: yesLife, 2022
Coronavirus Disease 2019 (COVID-19) is a highly infectious and pathogenic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Ming-Feng He   +11 more
doaj   +1 more source

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah   +5 more
doaj   +1 more source

Micelle Formation of Monoammonium Glycyrrhizinate

open access: yesJournal of Oleo Science, 2021
Monoammonium glycyrrhizinate is produced by the neutralization of glycyrrhizic acid from plant licorice with ammonia. In this study, the physicochemical properties of aqueous monoammonium glycyrrhizinate were investigated from the viewpoint of surface chemistry.
Keisuke, Matsuoka   +4 more
openaire   +3 more sources

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

open access: yesAdvanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova   +4 more
wiley   +1 more source

LC-MS/MS standardization and validation of glycyrrhizin from the roots of Taverniera cuneifolia: A potential alternative source of Glycyrrhiza glabra

open access: yesHeliyon, 2022
Glycyrrhizin is a triterpene glycoside derived from Glycyrrhiza glabra and related species which is a renowned phytochemical used to cure a variety of ailments such as inflammation, sore throat, hepatitis etc.
Padamnabhi S. Nagar   +2 more
doaj   +1 more source

Glycyrrhizin: A Review [PDF]

open access: yes, 2005
Glycyrrhizin is a triterpenoid saponin found in Glychyrrhiza glabra (licorice). Chemically, glycyrrhizin is a sulphated polysaccharide. It is considered to the active constituent of the drug and the standardization of licorice is based on glycyrrhizin ...
Singh, Amrit Pal
core   +1 more source

Samsoeum, a traditional herbal medicine, elicits apoptotic and autophagic cell death by inhibiting Akt/mTOR and activating the JNK pathway in cancer cells [PDF]

open access: yes, 2013
BACKGROUND: Samsoeum (SSE), a traditional herbal formula, has been widely used to treat cough, fever, congestion, and emesis for centuries. Recent studies have demonstrated that SSE retains potent pharmacological efficiency in anti-allergic and anti ...
Aeyung Kim, Jin Yeul Ma, Nam-Hui Yim
core   +1 more source

A leaf phenomics approach for estimating belowground traits in North American licorice

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Selective breeding over thousands of years has prioritized aboveground yield, with little regard for changes belowground. Roots underpin plant growth and resilience, but our knowledge of these critical structures lags behind that of aboveground structures.
Zachary N. Harris   +5 more
wiley   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

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