Results 51 to 60 of about 14,486 (271)

Glycyrrhizin (Glycyrrhizic Acid) HMGB1 (high mobility group box 1) inhibitor upregulate mitochondrial function in adipocyte, cell viability and in-silico study

open access: yesJournal of Saudi Chemical Society, 2022
Background: Mitochondrial plays a vital role in regulating obesity and related comorbidity. Targeting mitochondrial function could be a potent therapeutic approach to inhibit metabolic-related diseases like obesity, liver disease.
Md. Reyad-ul-Ferdous   +2 more
doaj   +1 more source

Metabolic Plasticity and Terpenoid Modulation in Zanthoxylum armatum Callus Cultures: Chemical Composition and Biotechnological Perspectives

open access: yesFlavour and Fragrance Journal, EarlyView.
Graphical abstract illustrating the metabolic dynamics and regulation of terpenoid production in Zanthoxylum armatum callus cultures. On the left, callus initiation and growth from explants are shown, followed by the establishment of suspension cultures.
Sumit Purohit   +11 more
wiley   +1 more source

Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma

open access: yesCellular Physiology and Biochemistry, 2017
Background: Currently, there is a global attempt to identify potential anti-cancer agents with low toxicity. Previous studies have found that glycyrrhizin exerts anti-cancer action with low toxicity through suppressing thromboxane A2 (TxA2) in lung ...
Qing-Ping Deng   +4 more
doaj   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Nutritional Composition, Antioxidant Activity And Anticarcinogenic Effect Of Typhonium Flagelliforme (Nicholson 1029) Extract In Rat [PDF]

open access: yes, 2000
Typhonium flagelliforme from the family Araceae is locally known as rodent tuber. It is being used traditionally in Malaysia to treat cancer. The major aim of this study was to investigate the effect of Typhonium flagelliforme crude extract on ...
Karuppiah, Thilakavathy
core  

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats

open access: yesBrazilian Journal of Medical and Biological Research, 2007
Massive hepatectomy associated with infection induces liver dysfunction, or even multiple organ failure and death. Glycyrrhizin has been shown to exhibit anti-oxidant and anti-inflammatory activities.
B. Tang, H. Qiao, F. Meng, X. Sun
doaj  

Recent advances in biosurfactant-based association colloids—Self-assembly in water

open access: yesFrontiers in Soft Matter, 2023
Recent studies of self-assembly in binary systems of bio-surfactants, either of microbial origin or saponins extracted from plants, are reviewed. Saponins in water reported in the first section include aescin, glycyrrhizin, and quillaja saponins, while ...
Thomas Hellweg   +2 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Mechanism of action of glycyrrhizin against Plasmodium falciparum [PDF]

open access: diamond, 2021
Maria de Nazaré Correia Soeiro   +2 more
openalex   +1 more source

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