Results 1 to 10 of about 56,183 (304)
Journal of Inflammation Research, 2021 Weixin Hou,1– 4 Xiaoyi Wei,1,2 Jiajun Liang,1– 4 Peng Fang,5 Chongyang Ma,1,2 Qiuyun Zhang,1,2,* Yanbin Gao3,4,* 1Department of Hepatology, School of Traditional Chinese Medicine, Capital Medical University, Beijing, People’s Republic of China ...
Hou W +6 more
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High mobility group box 1 inhibition by BoxA attenuates ovalbumin-induced allergic rhinitis in mice
Autoimmunity, 2022 This study was designed to evaluate the effects of BoxA on allergic rhinitis (AR). Ovalbumin (OVA)-induced AR mice model was employed and BoxA was administered to AR mice.
Liyan Yue +6 more
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Role of HMGB1 in Vitiligo: Current Perceptions and Future Perspectives
Clinical, Cosmetic and Investigational Dermatology, 2022 Guangmin Wei,1 Yinghao Pan,2 Jingying Wang,2 Xia Xiong,2 Yuanmin He,2 Jixiang Xu2 1Department of Dermatology, Medical Center Hospital of Qionglai City, Qionglai, Sichuan, People’s Republic of China; 2Department of Dermatology, The Affiliated Hospital of ...
Wei G +5 more
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Frontiers in Bioscience-LandmarkNeuroinflammation has emerged as a shared molecular mechanism in epilepsy and cognitive impairment, offering new insights into the complex interplay between immune responses and brain function.
Irma Wati Ngadimon +2 more
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Fingolimod Alleviates Inflammation after Cerebral Ischemia via HMGB1/TLR4/NF-κB Signaling Pathway
Journal of Integrative NeuroscienceBackground: Clinically, ischemic reperfusion injury is the main cause of stroke injury. This study aimed to assess the effectiveness of fingolimod in suppressing inflammation caused by ischemic brain injury and explore its pharmacological mechanisms ...
Yao Xing +5 more
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miR- 26a Sensitizes Melanoma Cells To Dabrafenib Via Targeting HMGB1-Dependent Autophagy Pathways
Drug Design, Development and Therapy, 2019 Yan Yu,1,* Niu Xiang,2,* Min Lin,2 Jin-Wen Huang,2 Jing Zhang,2 Bo Cheng,2 Chao Ji2 1Department of Dermatology, First Hospital of Jilin University, Changchun, Jilin 130021, People’s Republic of China; 2Department of Dermatology, The First ...
Yu Y +6 more
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Journal of Integrative NeuroscienceBackground: Most acute cerebral infarctions (ACI) may develop vascular dementia (VD), which involves almost all types of cognitive impairment. Unfortunately, there is currently no effective treatment for VD.
Hong Zhou +6 more
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Cancer Management and Research, 2020 Lei Chen,1 Kun Chi,2 Huaguo Xiang,3 Yan Yang4 1Department of Emergency Medicine, Xiang’an Hospital of Xiamen University, Xiamen, 361101, People’s Republic of China; 2Department of Nursing, Qingdao Municipal Hospital (Group), Qingdao 266071 ...
Chen L, Chi K, Xiang H, Yang Y
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High mobility group box 1 protein (HMGB1) stimulates the nuclear accumulation of p53
Biotechnology & Biotechnological Equipment, 2019 p53 is usually regarded as a tumour suppressor protein but its constant activation may result in pro-tumorigenic inflammation. The activation of p53 can be provoked by an increase in its concentration as a result of high level transcription, by ...
Maria Schröder +4 more
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Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): The expression of pro-inflammatory substances is closely related to various diseases. Genistein (GEN), a soy isoflavone, has been proven to inhibit the production of pro-inflammatory substances in macrophages.
Meimei Yang, Tianqi Zhang
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