Results 21 to 30 of about 44,760 (265)

A Comprehensive Overview of Organ Inflammatory Responses: Genesis, Possible Mechanisms, and Mediators of Inflammation [PDF]

open access: yesPharmaceutical Sciences, 2023
An immune system response known as inflammation can be carried on by a variety of things, such as infections, damaged cells, and noxious substances. These factors may cause acute or chronic inflammatory responses in the heart, pancreas, liver, kidney ...
Samar A. Antar   +4 more
doaj   +1 more source

microRNA-548b Suppresses Aggressive Phenotypes of Hepatocellular Carcinoma by Directly Targeting High-Mobility Group Box 1 mRNA [Retraction]

open access: yesCancer Management and Research, 2021
Yun Z, Meng F, Jiang P, Yue M, Li S. Cancer Manag Res. 2019;11:5821–5834. The Editor and Publisher of Cancer Management and Research wish to retract the published article.
Yun Z, Meng F, Jiang P, Yue M, Li S
doaj  

Electroacupuncture Pretreatment Ameliorates Anesthesia and Surgery-Induced Cognitive Dysfunction via Activation of an α7-nAChR Signal in Aged Rats

open access: yesNeuropsychiatric Disease and Treatment, 2021
Zhigang Wang,1,2 Tianlin Liu,1 Chunping Yin,1 Yanan Li,1 Fang Gao,1 Lili Yu,1 Qiujun Wang1 1Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People’s Republic of China; 2Department of Anesthesiology,
Wang Z   +6 more
doaj  

Regulation of HMGB1 release by autophagy [PDF]

open access: yesAutophagy, 2009
The characteristics of tumor cell killing by an anticancer agent can determine the long-term effectiveness of the treatment. For example, if dying tumor cells release the immune modulator HMGB1 after treatment with anticancer drugs, they can activate a tumor-specific immune response that boosts the effectiveness of the initial treatment.
Jacqueline, Thorburn   +2 more
openaire   +2 more sources

Role of HMGB1 in cardiovascular diseases [PDF]

open access: yesCurrent Opinion in Pharmacology, 2006
A nuclear protein, high mobility group box 1 (HMGB1), is released passively by necrotic cells, and actively by macrophages/monocytes in response to exogenous and endogenous inflammatory stimuli. After binding to the receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4), HMGB1 activates vascular endothelial cells and ...
Wei, Li, Andrew E, Sama, Haichao, Wang
openaire   +2 more sources

Korelasi Kadar HMGB1 dalam Serum dengan Derajat Fungsional Neurologik yang Diukur dengan NIHSS pada Pasien Stroke Trombotik Akut

open access: yesAksona, 2021
Pendahuluan: High mobility group box 1 (HMGB1), akhir-akhir ini diketahui sebagai salah satu mediator yang memicu proses inflamasi setelah terjadi iskemia di otak.
Aris Widayati, Mohammad Saiful Islam
doaj   +1 more source

Targeting HMGB1 in the treatment of sepsis [PDF]

open access: yesExpert Opinion on Therapeutic Targets, 2014
Sepsis refers to the host's deleterious and non-resolving systemic inflammatory response to microbial infections and represents the leading cause of death in the intensive care unit. The pathogenesis of sepsis is complex, but partly mediated by a newly identified alarmin molecule, the high mobility group box 1 (HMGB1).Here we review the evidence that ...
Haichao, Wang   +2 more
openaire   +2 more sources

High Mobility Group Box – 1 in Patients with Bacterial Septic Arthritis of the Knee: A Controlled Prospective Study

open access: yesErciyes Medical Journal, 2020
Objective: High mobility group Box–1 (HMGB-1) is related to inflammation and many kinds of arthritic diseases. Septic arthritis is acute infectious arthritis with potentially devastating outcomes and needs to be diagnosed and treated in an emergent ...
Alper Öztürk   +6 more
doaj   +1 more source

Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities

open access: yesJournal of Investigative Surgery, 2022
Aim Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including interleukin 6 (IL-6), C-reactive ...
Volkan Solmaz   +4 more
doaj   +1 more source

Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer

open access: yesCancer Management and Research, 2021
Yuanli Huang,1,2 Guanghui Zhang,1,2 Qing Zhu,1 Xia Wu,3 Ligao Wu1 1Department of Pathology, the First Affiliated Hospital of Bengbu Medical College, Bengbu City, Anhui Province, People’s Republic of China; 2Graduate School of Bengbu Medical College ...
Huang Y, Zhang G, Zhu Q, Wu X, Wu L
doaj  

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