Results 41 to 50 of about 51,717 (306)

Regulation of HMGB1 release by autophagy [PDF]

Autophagy, 2009
The characteristics of tumor cell killing by an anticancer agent can determine the long-term effectiveness of the treatment. For example, if dying tumor cells release the immune modulator HMGB1 after treatment with anticancer drugs, they can activate a tumor-specific immune response that boosts the effectiveness of the initial treatment.
Jacqueline, Thorburn, Arthur E, Frankel, Andrew, Thorburn   +2 more
openaire   +2 more sources

Korelasi Kadar HMGB1 dalam Serum dengan Derajat Fungsional Neurologik yang Diukur dengan NIHSS pada Pasien Stroke Trombotik Akut

Aksona, 2021
Pendahuluan: High mobility group box 1 (HMGB1), akhir-akhir ini diketahui sebagai salah satu mediator yang memicu proses inflamasi setelah terjadi iskemia di otak.
Aris Widayati, Mohammad Saiful Islam
doaj   +1 more source

Role of HMGB1 in cardiovascular diseases [PDF]

Current Opinion in Pharmacology, 2006
A nuclear protein, high mobility group box 1 (HMGB1), is released passively by necrotic cells, and actively by macrophages/monocytes in response to exogenous and endogenous inflammatory stimuli. After binding to the receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4), HMGB1 activates vascular endothelial cells and ...
Wei, Li, Andrew E, Sama, Haichao, Wang
openaire   +2 more sources

High Mobility Group Box – 1 in Patients with Bacterial Septic Arthritis of the Knee: A Controlled Prospective Study

Erciyes Medical Journal, 2020
Objective: High mobility group Box–1 (HMGB-1) is related to inflammation and many kinds of arthritic diseases. Septic arthritis is acute infectious arthritis with potentially devastating outcomes and needs to be diagnosed and treated in an emergent ...
Alper Öztürk, Yener Bilgetekin, Halis Atıl Atilla, Mesut Emlek, Önder Ersan, Esra Çetin, Ali Yalçındağ   +6 more
doaj   +1 more source

Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities

Journal of Investigative Surgery, 2022
Aim Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including interleukin 6 (IL-6), C-reactive ...
Volkan Solmaz, Mahmut Kaya, Fatma Betul Uslu, Ozum Atasoy, Oytun Erbaş   +4 more
doaj   +1 more source

Targeting HMGB1 in the treatment of sepsis [PDF]

Expert Opinion on Therapeutic Targets, 2014
Sepsis refers to the host's deleterious and non-resolving systemic inflammatory response to microbial infections and represents the leading cause of death in the intensive care unit. The pathogenesis of sepsis is complex, but partly mediated by a newly identified alarmin molecule, the high mobility group box 1 (HMGB1).Here we review the evidence that ...
Haichao, Wang, Mary F, Ward, Andrew E, Sama   +2 more
openaire   +2 more sources

Long non-coding RNA LINC00704 promotes cell proliferation, migration, and invasion in papillary thyroid carcinoma via miR-204-5p/HMGB1 axis

Open Life Sciences, 2020
Papillary thyroid carcinoma (PTC) is a common malignancy worldwide. LncRNA LINC00704 (mitotically associated long non-coding RNA) was reported as a crucial regulator in PTC.
Lin Yihui, Jiang Jianjia
doaj   +1 more source

Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A [PDF]

, 2013
© 2013 Matsumiya et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Helen McShane (80704), Pathan, Ansar A, Stylianou, E, Lang, Z, Stephanie A. Harris (429956), Elena Stylianou (292312), Matsumiya, Magali, Griffiths Kristin, Lang Zoe, McShane Helen, Meyer, Joel, Magali Matsumiya, Griffiths, Kristin, Zoe Lang (429954), Lang, Zoe, Ansar A Pathan, Meyer, J, Angela M. Minassian (345365), Magali Matsumiya (429952), Fletcher Helen, Harris, Stephanie A, Rowland Rosalind, Meyer Joel, Kristin Griffiths (429953), Joel Meyer, Harris, SA, McShane, H, Fletcher, Helen, McShane, Helen, Minassian, Angela M, Zoe Lang, Rowland, Rosalind, Matsumiya Magali, Minassian Angela M., Angela M Minassian, Kristin Griffiths, Pathan Ansar A., Joel Meyer (429955), Helen Fletcher, Harris Stephanie A., Rowland, R, Rosalind Rowland, Matsumiya, M, Pathan, AA, Fletcher, H, Minassian, AM, Helen Fletcher (249210), Rosalind Rowland (429957), Helen McShane, Griffiths, K, Elena Stylianou, Stephanie A Harris, Ansar A. Pathan (80697), Stylianou, Elena, Stylianou Elena   +54 more
core   +1 more source

Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer

Cancer Management and Research, 2021
Yuanli Huang,1,2 Guanghui Zhang,1,2 Qing Zhu,1 Xia Wu,3 Ligao Wu1 1Department of Pathology, the First Affiliated Hospital of Bengbu Medical College, Bengbu City, Anhui Province, People’s Republic of China; 2Graduate School of Bengbu Medical College ...
Huang Y, Zhang G, Zhu Q, Wu X, Wu L
doaj  

Role of Low Frequency Repetitive Trans Cranial Magnetic Stimulation in Drug Resistant Epilepsy Clinical, Laboratory and Neurophysiology Study [PDF]

International Journal of Medical Arts
Background: Drug-resistant epilepsy [DRE] poses significant challenges in management, affecting a huge number of epileptic patients despite the availability of antiepileptic medications.
Asmaa Mohamed Abd Elwaged, Hoda M Masoud, Rasha El-bialy Elsharkawy, Sarah Younes Abdelaziz   +3 more
doaj   +1 more source