Results 41 to 50 of about 56,183 (304)

Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities

Journal of Investigative Surgery, 2022
Aim Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including interleukin 6 (IL-6), C-reactive ...
Volkan Solmaz, Mahmut Kaya, Fatma Betul Uslu, Ozum Atasoy, Oytun Erbaş   +4 more
doaj   +1 more source

HMGB1 is a potent trigger of arthritis [PDF]

Journal of Internal Medicine, 2004
Abstract.Rheumatoid arthritis is a chronic inflammatory disease characterized by synovial inflammation and structural damage of joints. Although the cause of rheumatoid arthritis (RA) remains unknown, the excessive production of proinflammatory cytokines such as tumour necrosis factor (TNF) and interleukin‐1 (IL‐1) by intra‐articular macrophages ...
U, Andersson, H, Erlandsson-Harris
openaire   +2 more sources

Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A [PDF]

, 2013
© 2013 Matsumiya et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Helen McShane (80704), Pathan, Ansar A, Stylianou, E, Lang, Z, Stephanie A. Harris (429956), Elena Stylianou (292312), Matsumiya, Magali, Griffiths Kristin, Lang Zoe, McShane Helen, Meyer, Joel, Magali Matsumiya, Griffiths, Kristin, Zoe Lang (429954), Lang, Zoe, Ansar A Pathan, Meyer, J, Angela M. Minassian (345365), Magali Matsumiya (429952), Fletcher Helen, Harris, Stephanie A, Rowland Rosalind, Meyer Joel, Kristin Griffiths (429953), Joel Meyer, Harris, SA, McShane, H, Fletcher, Helen, McShane, Helen, Minassian, Angela M, Zoe Lang, Rowland, Rosalind, Matsumiya Magali, Minassian Angela M., Angela M Minassian, Kristin Griffiths, Pathan Ansar A., Joel Meyer (429955), Helen Fletcher, Harris Stephanie A., Rowland, R, Rosalind Rowland, Matsumiya, M, Pathan, AA, Fletcher, H, Minassian, AM, Helen Fletcher (249210), Rosalind Rowland (429957), Helen McShane, Griffiths, K, Elena Stylianou, Stephanie A Harris, Ansar A. Pathan (80697), Stylianou, Elena, Stylianou Elena   +54 more
core   +1 more source

Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer

Cancer Management and Research, 2021
Yuanli Huang,1,2 Guanghui Zhang,1,2 Qing Zhu,1 Xia Wu,3 Ligao Wu1 1Department of Pathology, the First Affiliated Hospital of Bengbu Medical College, Bengbu City, Anhui Province, People’s Republic of China; 2Graduate School of Bengbu Medical College ...
Huang Y, Zhang G, Zhu Q, Wu X, Wu L
doaj  

Role of Low Frequency Repetitive Trans Cranial Magnetic Stimulation in Drug Resistant Epilepsy Clinical, Laboratory and Neurophysiology Study [PDF]

International Journal of Medical Arts
Background: Drug-resistant epilepsy [DRE] poses significant challenges in management, affecting a huge number of epileptic patients despite the availability of antiepileptic medications.
Asmaa Mohamed Abd Elwaged, Hoda M Masoud, Rasha El-bialy Elsharkawy, Sarah Younes Abdelaziz   +3 more
doaj   +1 more source

Long non-coding RNA LINC00704 promotes cell proliferation, migration, and invasion in papillary thyroid carcinoma via miR-204-5p/HMGB1 axis

Open Life Sciences, 2020
Papillary thyroid carcinoma (PTC) is a common malignancy worldwide. LncRNA LINC00704 (mitotically associated long non-coding RNA) was reported as a crucial regulator in PTC.
Lin Yihui, Jiang Jianjia
doaj   +1 more source

HMGB1 loves company [PDF]

Journal of Leukocyte Biology, 2009
Abstract HMGB1 outside of a cell is both a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it forms with other molecules. HMGB1, outside of a cell, is a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it ...
openaire   +3 more sources

Peripheral HMGB1-induced hyperalgesia in mice: Redox state-dependent distinct roles of RAGE and TLR4

Journal of Pharmacological Sciences, 2016
Nuclear HMGB1 that contains 3 cysteine residues is acetylated and secreted to the extracellular space, promoting inflammation via multiple molecules such as RAGE and TLR4.
Daichi Yamasoba, Maho Tsubota, Risa Domoto, Fumiko Sekiguchi, Hiroyuki Nishikawa, Keyue Liu, Masahiro Nishibori, Hiroyasu Ishikura, Tetsushi Yamamoto, Atsushi Taga, Atsufumi Kawabata   +10 more
doaj   +1 more source

HMGB1 Mediates Microglia-Astrocyte/Neuron Crosstalk and Pyroptosis by the TLR4/NF-κB Pathway in Multiple Sclerosis

Frontiers in Bioscience-Landmark
Background: Multiple sclerosis (MS) is characterized as a chronic inflammatory autoimmune disorder affecting the central nervous system (CNS).
Yang Feng, Liang Wang, Zhuofeng Mao, Weiping Wang   +3 more
doaj   +1 more source

HMGB1-mediated apoptosis and autophagy in ischemic heart diseases

Vascular Biology, 2019
Acute myocardial infarction (MI) and its consequences are the most common and lethal heart syndromes worldwide and represent a significant health problem.
Eleonora Foglio, Laura Pellegrini, Antonia Germani, Matteo Antonio Russo, Federica Limana   +4 more
doaj   +1 more source