Results 31 to 40 of about 51,717 (306)

Integrative Atherosclerosis Treatment: Harnessing Herbal and Synthetic HMGB1 Inhibitors [PDF]

open access: yesResearch Journal of Pharmacognosy
Human group box protein 1 (HMGB1) is a nuclear protein critical in various cellular processes. It is released in response to stress, infection, or tissue damage and acts as a danger signal, triggering immunological responses.
Ceaser Wankumbu Silumbwe*   +6 more
doaj   +1 more source

Correlation between MMP-9 and extracellular cytokine HMGB1 in prediction of human ischemic stroke outcome [PDF]

open access: yes, 2014
Ischemic stroke (IS) outcome predictors include clinical features, biochemical parameters and some risk factors. The relations between two main players in the ischemic brain, MMPs and HMGB1, were estimated in the plasma of ischemic stroke patients ...
Kalandadze, Iagor   +7 more
core   +1 more source

Electroacupuncture inhibits the expression of HMGB1/RAGE and alleviates injury to the primary motor cortex in rats with cerebral ischemia

open access: yesTranslational Neuroscience, 2023
The high-mobility group box 1 (HMGB1)/receptor for advanced glycation end products (RAGE) signaling pathway holds promise as a potential therapeutic target for ischemic brain injury. The effects of FPS-ZM1 and electroacupuncture (EA) on activation of the
Nie Zeyin   +3 more
doaj   +1 more source

The Effect of PD-1 Inhibitor Combined with Irradiation on HMGB1-Associated Inflammatory Cytokines and Myocardial Injury

open access: yesJournal of Inflammation Research, 2022
Jie Bai,1– 3,* Bibo Wu,1– 3,* Shasha Zhao,1– 3,* Gang Wang,1– 3,* Shengfa Su,1– 3 Bing Lu,1– 3 Yinxiang Hu,1– 3 Yichao Geng,1,3 Zhengneng Guo,1– 3 Jun Wan,2,3 Weiwei OuYang,1– 3 Cheng Hu,1– 3 Jie Liu1– 3 1Department of Oncology, The ...
Bai J   +12 more
doaj  

MicroRNA-98 inhibition accelerates the development of atherosclerosis via regulation of dysfunction of endothelial cell

open access: yesClinical and Experimental Hypertension, 2023
Background Atherosclerosis has been recognized as a chronic inflammation initiated by dysfunction of endothelial cell that contributes to the increased morbidity and mortality of severe cardiovascular events.
Huai Yu, Hui Cao, Hang Yu
doaj   +1 more source

HMGB1 loves company [PDF]

open access: yesJournal of Leukocyte Biology, 2009
Abstract HMGB1 outside of a cell is both a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it forms with other molecules. HMGB1, outside of a cell, is a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it ...
openaire   +3 more sources

A Comprehensive Overview of Organ Inflammatory Responses: Genesis, Possible Mechanisms, and Mediators of Inflammation [PDF]

open access: yesPharmaceutical Sciences, 2023
An immune system response known as inflammation can be carried on by a variety of things, such as infections, damaged cells, and noxious substances. These factors may cause acute or chronic inflammatory responses in the heart, pancreas, liver, kidney ...
Samar A. Antar   +4 more
doaj   +1 more source

The Role of HMGB1 in Rheumatic Diseases [PDF]

open access: yesFrontiers in Immunology, 2022
HMGB1, a highly conserved non-histone nuclear protein, is widely expressed in mammalian cells. HMGB1 in the nucleus binds to the deoxyribonucleic acid (DNA) to regulate the structure of chromosomes and maintain the transcription, replication, DNA repair, and nucleosome assembly.
Yuanji Dong, Bingxia Ming, Lingli Dong
openaire   +3 more sources

microRNA-548b Suppresses Aggressive Phenotypes of Hepatocellular Carcinoma by Directly Targeting High-Mobility Group Box 1 mRNA [Retraction]

open access: yesCancer Management and Research, 2021
Yun Z, Meng F, Jiang P, Yue M, Li S. Cancer Manag Res. 2019;11:5821–5834. The Editor and Publisher of Cancer Management and Research wish to retract the published article.
Yun Z, Meng F, Jiang P, Yue M, Li S
doaj  

Electroacupuncture Pretreatment Ameliorates Anesthesia and Surgery-Induced Cognitive Dysfunction via Activation of an α7-nAChR Signal in Aged Rats

open access: yesNeuropsychiatric Disease and Treatment, 2021
Zhigang Wang,1,2 Tianlin Liu,1 Chunping Yin,1 Yanan Li,1 Fang Gao,1 Lili Yu,1 Qiujun Wang1 1Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People’s Republic of China; 2Department of Anesthesiology,
Wang Z   +6 more
doaj  

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