Results 1 to 10 of about 2,522,082 (192)
Pharmaceuticals, 2023 Licorice, a natural medicine derived from the roots and rhizomes of Glycyrrhiza species, possesses a wide range of therapeutic applications, including antiviral properties. Glycyrrhizic acid (GL) and glycyrrhetinic acid (GA) are the most important active
Jiawei Zuo +3 more
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Heliyon, 2023 Influences of Glycyrrhetinic acid on expression of inflammatory factors in interleukin (IL)-1β-induced SW982 cells and its anti-inflammatory effects were discussed in this study.
Yang Song +7 more
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Network Pharmacology Analysis of Glycyrrhetinic Acid in Metabolic Dysfunction-Associated Steatotic Liver Disease [PDF]
MetabolitesBackground: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multifactorial disorder driven by tightly interconnected metabolic, inflammatory, and lipid dysregulation pathways.
Osmar Antonio Jaramillo-Morales +7 more
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Pharmaceutics, 2021 Glycyrrhizic acid and its hydrolyzed metabolite 18β-glycyrrhetinic acid, obtained from the plant Glycyrrhiza glabra, have numerous pharmacological activities, such as anti-inflammatory, anti-ulcerative, antiallergic, immunomodulatory, antiviral ...
Luciano A. Stecanella +5 more
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Glycyrrhetinic acid reduces lung inflammation caused by pneumococcal infection by reducing the toxicity of pneumolysin [PDF]
HeliyonObjective: In this study, to provide new methods for the treatment of Streptococcus pneumoniae infection, we aimed to describe the anti-inflammatory and antibacterial value of glycyrrhetinic acid on the basis of its inhibitory effect on bacterial growth (
Yan Xu +6 more
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Reengineering glycyrrhetinic acid into a therapeutic oligomer for targeted tumor therapy with cardioprotection [PDF]
Journal of NanobiotechnologyTo overcome the inherent limitations of conventional nanocarriers such as therapeutic inefficacy and suboptimal drug loading capacity, a novel “polymeric nanodrug” strategy was developed.
Zixin Wang +10 more
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18β-Glycyrrhetinic Acid Protects against Cholestatic Liver Injury in Bile Duct-Ligated Rats
Antioxidants, 2022 18β-Glycyrrhetinic acid is a nutraceutical agent with promising hepatoprotective effects. Its protective mechanisms against cholestatic liver injury were further investigated in a rodent model of extrahepatic cholestasis caused by Bile Duct Ligation (BDL)
Pin-Ho Pan +7 more
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Journal of Integrative Agriculture, 2023 Natural products have long been a crucial source of, or provided inspiration for new agrochemical discovery. Naturally occurring 18β-glycyrrhetinic acid shows broad-spectrum bioactivities and is a potential skeleton for novel drug discovery.
Ying-lian SONG +9 more
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Parasite, 2021 This study evaluated the in vitro anthelmintic activity of a liquorice (Glycyrrhiza glabra) root aqueous extract and of glycyrrhetinic acid at 30, 10, 5, 1, and 0.5 mg/mL against sheep gastrointestinal nematodes (GINs), using the egg hatch test (EHT ...
Maestrini Michela +3 more
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Molecules, 2022 Nowadays, subcritical water extraction (SWE) techniques are extensively investigated worldwide, while the thermal reactions that inevitably occur under subcritical water conditions are rarely studied.
Rui Fan, Yanxiang Gao
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