Results 11 to 20 of about 6,171 (143)

Maillard and Hydrolytic Reactions in Subcritical Water Extraction of Bioactive Compounds from Licorice

Molecules, 2022
Nowadays, subcritical water extraction (SWE) techniques are extensively investigated worldwide, while the thermal reactions that inevitably occur under subcritical water conditions are rarely studied.
Rui Fan, Yanxiang Gao
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Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity

Molecules, 2021
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water.
Wei-Yan Quan, Song-Zhi Kong, Si-Dong Li, Hua-Zhong Liu, Qian-Qian Ouyang, Yong-Mei Huang, Hui Luo   +6 more
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Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

Molecules, 2023
Acetylated triterpenoids betulin, oleanolic acid, ursolic acid, and glycyrrhetinic acid were converted into their succinyl-spacered acetazolamide conjugates.
Toni C. Denner, Niels Heise, Julian Zacharias, Oliver Kraft, Sophie Hoenke, René Csuk   +5 more
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Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid

Beilstein Journal of Organic Chemistry, 2020
In the present study, a practical method to prepare piperazinyl amides of 18β-glycyrrhetinic acid was developed. Two main procedures for the construction of important intermediate 8 are discussed.
Dong Cai, ZhiHua Zhang, Yufan Meng, KaiLi Zhu, LiYi Chen, ChangXiang Yu, ChangWei Yu, ZiYi Fu, DianShen Yang, YiXia Gong   +9 more
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Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins

Acta Pharmaceutica Sinica B, 2019
Members of the RAS proto-oncogene superfamily are indispensable molecular switches that play critical roles in cell proliferation, differentiation, and cell survival.
Yuan Zhang, Zhihua Wang, Xiaoyao Ma, Shengnan Yang, Xueyan Hu, Jin Tao, Yuanyuan Hou, Gang Bai   +7 more
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Database-aided UHPLC-Q-orbitrap MS/MS strategy putatively identifies 52 compounds from Wushicha Granule to propose anti-counterfeiting quality-markers for pharmacopoeia

Chinese Medicine, 2023
Wushicha Granule, an over-the-counter-drug (OTC) prescription, consists of 19 traditional Chinese herbals medicines (CHMs), such as Chaihu, Hongcha, Chuanxiong, Houpo, and Gancao.
Xican Li, Shaoman Chen, Jingyuan Zeng, Rongxin Cai, Yilan Liang, Chuanbin Chen, Ban Chen, Chunhou Li   +7 more
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Design, Synthesis, and Biological Activity of 18β-Glycyrrhetinic Acid Derivatives and Their Metal Complexes

Medical Sciences Forum, 2022
The increasing morbidity and mortality caused by infections with pathogenic bacteria (fungus or bacteria) have highlighted an urgent requirement for developing novel anti-bacterial agents to protect the health and integrity of human life.
Caiyun Yang, Xinhui Pan, Xiaoda Yang
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A SIMPLE AND RAPID METHOD FOR SIMULTANEOUS ESTIMATION OF GLYCYRRHETINIC ACID AND PIPERINE BY HPTLC IN A HERBOMINERAL FORMULATION [PDF]

Journal of Advanced Pharmaceutical Technology & Research, 2010
Many of the traditional herbal formulations contain extracts of Piper longum and Glycyrrhiza glabra, piperine and glycyrrhetinic acid respectively, being active constituents of these two herbs.
Ashish Trivedi, S. H. Mishra
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The therapeutic effect of glycyrrhizic acid compound ointment on imiquimod-induced psoriasis-like disease in mice.

PLoS ONE, 2023
Glycyrrhetinic acid, a drug with anti-inflammatory effects, enhanced the activity of antipsoriatic efficacy. In this research, an ointment with glycyrrhetinic acid was prepaired as the major component and several other herbal monomers (astilbin, osthole,
Yanwen Zhang, Qian Wang, Shuangyong Sun, Lingyan Jiang   +3 more
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Study of an Acid-Free Technique for the Preparation of Glycyrrhetinic Acid from Ammonium Glycyrrhizinate in Subcritical Water

Natural Product Communications, 2015
The aim of this work was to study an application of a previously developed expedient acid-free technique for the preparation of glycyrrhetinic acid from ammonium glycyrrhizinate that requires no use of acids and toxic organic solvents.
Anna V. Lekar, Sergey N. Borisenko, Elena V. Vetrova, Olga V. Filonova, Elena V. Maksimenko, Nikolai I. Borisenko, Vladimir I. Minkin   +6 more
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