Results 11 to 20 of about 2,522,082 (192)

Glycyrrhetinic acid and its derivatives in infectious diseases

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2016
Introduction. Licorice or liquorice (Glycyrrhiza glabra, Leguminosae) is a perennial plant naturally occurring or cultivated in Europe and Asia. It was appreciated by many ancient cultures, and was employed within Arabic medicine and (beginning in the ...
Langer Dominik   +2 more
doaj   +3 more sources

Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives [PDF]

open access: yesMolecules, 2019
A new series of glycyrrhetinic acid derivatives has been synthesized via the introduction of different heterocyclic rings conjugated with an α,β-unsaturated ketone in its ring A.
Daniela P. S. Alho   +3 more
doaj   +3 more sources

Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity

open access: yesMolecules, 2021
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water.
Wei-Yan Quan   +6 more
doaj   +1 more source

Bioactive microbial metabolites from glycyrrhetinic acid

open access: yes, 2009
Biotransformation of 18β-glycyrrhetinic acid, using Absidia pseudocylinderospora ATCC 24169, Gliocladium viride ATCC 10097 and Cunninghamella echinulata ATCC 8688a afforded seven metabolites, which were identified by different spectroscopic techniques ...
Maatooq, Galal T.   +3 more
core   +4 more sources

Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

open access: yesMolecules, 2023
Acetylated triterpenoids betulin, oleanolic acid, ursolic acid, and glycyrrhetinic acid were converted into their succinyl-spacered acetazolamide conjugates.
Toni C. Denner   +5 more
doaj   +1 more source

Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid

open access: yesBeilstein Journal of Organic Chemistry, 2020
In the present study, a practical method to prepare piperazinyl amides of 18β-glycyrrhetinic acid was developed. Two main procedures for the construction of important intermediate 8 are discussed.
Dong Cai   +9 more
doaj   +1 more source

Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins

open access: yesActa Pharmaceutica Sinica B, 2019
Members of the RAS proto-oncogene superfamily are indispensable molecular switches that play critical roles in cell proliferation, differentiation, and cell survival.
Yuan Zhang   +7 more
doaj   +1 more source

Design, Synthesis, and Biological Activity of 18β-Glycyrrhetinic Acid Derivatives and Their Metal Complexes

open access: yesMedical Sciences Forum, 2022
The increasing morbidity and mortality caused by infections with pathogenic bacteria (fungus or bacteria) have highlighted an urgent requirement for developing novel anti-bacterial agents to protect the health and integrity of human life.
Caiyun Yang, Xinhui Pan, Xiaoda Yang
doaj   +1 more source

A SIMPLE AND RAPID METHOD FOR SIMULTANEOUS ESTIMATION OF GLYCYRRHETINIC ACID AND PIPERINE BY HPTLC IN A HERBOMINERAL FORMULATION [PDF]

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2010
Many of the traditional herbal formulations contain extracts of Piper longum and Glycyrrhiza glabra, piperine and glycyrrhetinic acid respectively, being active constituents of these two herbs.
Ashish Trivedi, S. H. Mishra
doaj   +2 more sources

Database-aided UHPLC-Q-orbitrap MS/MS strategy putatively identifies 52 compounds from Wushicha Granule to propose anti-counterfeiting quality-markers for pharmacopoeia

open access: yesChinese Medicine, 2023
Wushicha Granule, an over-the-counter-drug (OTC) prescription, consists of 19 traditional Chinese herbals medicines (CHMs), such as Chaihu, Hongcha, Chuanxiong, Houpo, and Gancao.
Xican Li   +7 more
doaj   +1 more source

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